3.4.22.B1: vignain
This is an abbreviated version!
For detailed information about vignain, go to the full flat file.
Word Map on EC 3.4.22.B1
-
3.4.22.B1
-
neuroblastoma
-
mungo
-
sk-n-sh
-
neuroblast
-
kdel-tailed
-
papain-type
-
mycn-amplified
-
neuroblast-like
-
ricinosomes
- 3.4.22.B1
- neuroblastoma
- mungo
-
sk-n-sh
- neuroblast
-
kdel-tailed
-
papain-type
-
mycn-amplified
-
neuroblast-like
-
ricinosomes
Reaction
hydrolysis of proteins, such as azocasein. Preferential cleavage: Asn-/-Xaa in small molecule substrates such as Boc-Asn-/-OPHNO2 =
Synonyms
Bean endopeptidase, C01.010, CP1, CP2, CPPh1, Cyp15a, CysEp, cysteine endopeptidase, cysteine protease, cysteine proteinase, SH-EP, sulfhydryl-endopeptidase, VmPE-1
ECTree
Advanced search results
Posttranslational Modification
Posttranslational Modification on EC 3.4.22.B1 - vignain
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
proteolytic modification
-
the enzyme has a C-terminal propeptide of 1000 Da that contains an endoplasmic reticulum retention signal, KDEL. The KDEL-tail functions to store SH-EP as a transient zymogen in the lumen of the ER, and the C-terminal propeptide is thought to be removed within the ER or immediately after exit from the ER
proteolytic modification
-
the enzyme is synthesized on membrane-bound ribosomes as an inactive 45000 Da precursor, which is cotranslationally processed to a 43000 Da intermediate through cleavage of the signal sequence. The 43000 Da intermediate of SH-EP is further processed to the 33000 Da mature enzyme via 39000 Da and 36000 Da intermediates
proteolytic modification
-
the N-terminal post-translational processing of SH-EP is mediated by at least two processing enzymes, designated VmPE-1 and VmPE-2