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3.4.22.8: clostripain

This is an abbreviated version!
For detailed information about clostripain, go to the full flat file.

Reaction

Preferential cleavage: Arg-/-, including Arg-/-Pro, but not Lys- =

Synonyms

alpha-clostridipain, alpha-clostripain, CLO, clostridiopeptidase, clostridiopeptidase B, Clostridium histolyticum proteinase B, clostripain-like protease, EC 3.4.4.20, proteinase, Clostridium histolyticum, B

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.8 clostripain

Turnover Number

Turnover Number on EC 3.4.22.8 - clostripain

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
22.53
Ac-L-Lys-4-nitroanilide
-
-
91 - 643
alpha-benzoyl-Arg ethyl ester
1170
benzoyl-Arg ethyl ester
-
-
109.3
benzoyl-L-Arg-4-nitroanilide
-
-
824
maleyl-Tyr-Arg ethyl ester
-
-
87
N-benzoyl-L-Arg amide
-
-
38.8 - 69.5
Nalpha-benzoyl-L-arginine-4-nitroanilide
22
Nalpha-benzoyl-L-Lys methyl ester
-
-
10
Nalpha-p-tosyl-L-Arg amide
-
-
9.8
Nalpha-p-tosyl-L-Arg methyl ester
-
-
31
p-Nitrophenyl p-guanidinobenzoate
-
-
86
p-toluenesulfonyl-L-Arg methyl ester
-
-
additional information
additional information
-
effect of pH-value on the turnover-number for hydrolysis of alpha-benzoyl-Arg ethyl ester, effect of temperature on turnover numbers
-