3.4.22.71: sortase B

This is an abbreviated version!
For detailed information about sortase B, go to the full flat file.

Reaction

The enzyme catalyses a cell wall sorting reaction in which a surface protein with a sorting signal containing a NPXTN motif is cleaved. The resulting threonine carboxyl end of the protein is covalently attached to a pentaglycine cross-bridge of peptidoglycan. =

Synonyms

CD630_27180, class B sortase, CPE0513, sortase B, Spy0129, SrtB, StrB

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.71 sortase B

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1561	AA Sequence
2	Application
1	CAS Registry Number
8	Cloned(Commentary)
8	Crystallization (Commentary)
8	General Information
9	IC50 Value
16	Inhibitors
3	Metals/Ions
7	Natural Substrates/ Products (Substrates)
45	Organism
6	PDB ID
2	pH Optimum
1	pH Range
15	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
31	Reference
23	Substrates and Products (Substrate)
2	Subunits
19	Synonyms
1	Temperature Optimum [°C]

IC50 Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

IC50 Value on EC 3.4.22.71 - sortase B

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to IC50 Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.03837

galangin

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.03837 mM, no antibacterial activity against Staphylococcus aureus

664280

0.1136

galangin-3-methyl ether

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.1136 mM, no antibacterial activity against Staphylococcus aureus

664280

0.04335

isorhamnetin

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.04335 mM, no antibacterial activity against Staphylococcus aureus

664280

0.02455

kaempferol

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.02455 mM, no antibacterial activity against Staphylococcus aureus

664280

0.00854

morin

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.00854 mM, no antibacterial activity against Staphylococcus aureus

664280

0.03689

myricetin

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.03689 mM, no antibacterial activity against Staphylococcus aureus

664280

0.03328

quercetin

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.03328 mM, no antibacterial activity against Staphylococcus aureus

664280

0.0603

quercetin-3,3'-dimethyl ether

Staphylococcus aureus

-

IC50 for recombinant SrtB(DELTA30): 0.0603 mM, no antibacterial activity against Staphylococcus aureus

664280

additional information

coptisine

Staphylococcus aureus

-

IC50 value is 0.0087 mg/ml

754800