3.4.22.7: asclepain

This is an abbreviated version!
For detailed information about asclepain, go to the full flat file.

Reaction

Similar to that of papain =

Synonyms

asclepain c, asclepain cI, asclepain cII, asclepain f, papain-like endopeptidase, papain-like protease

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.7 asclepain

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Results	in table
3	AA Sequence
2	Application
1	CAS Registry Number
1	Cloned(Commentary)
1	Crystallization (Commentary)
1	General Information
9	Inhibitors
1	kcat/KM [mM/s]
15	KM Value [mM]
2	Localization
21	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
20	Organism
7	pH Optimum
3	pH Range
6	pH Stability
6	pI Value
1	Posttranslational Modification
8	Purification (Commentary)
1	Reaction
1	Reaction Type
18	Reference
19	Source Tissue
6	Specific Activity [micromol/min/mg]
59	Substrates and Products (Substrate)
16	Subunits
14	Synonyms
1	Temperature Optimum [°C]
8	Temperature Stability [°C]
12	Turnover Number [1/s]

pH Range

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pH Range on EC 3.4.22.7 - asclepain

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5 - 9

Asclepias glaucescens

-

pH 5.0: about 70% of maximal activity, pH 9.0: about 30% of maximal activity, hydrolysis of N-benzoyl-L-Arg ethyl ester, asclepain Ag7

81576

7.5 - 9

Asclepias curassavica

-

-

670802

9.4 - 10.2

Asclepias curassavica

B7VF64, B7VF65

asclepain cII shows maximum activity within the range of pH 9.4 and 10.2 with casein as substrate

695296