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3.4.22.65: peptidase 1 (mite)

This is an abbreviated version!
For detailed information about peptidase 1 (mite), go to the full flat file.

Word Map on EC 3.4.22.65

Reaction

broad endopeptidase specificity =

Synonyms

allergen Der f 1, allergen Der f1, allergen Der p, allergen Der p 1, allergen Der p1, CO1.073, Der f 1, Der f1, Der p 1, Der p 7, Der p1, dust mite allergen Der p 7, dust mite peptidase allergen Der p 1, house dust mite allergen, house dust mite allergens, major house dust mite allergen, mite allergen, mite major group 1 allergens, pro-Der f1, ProDer f 1, ProDer p 1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.65 peptidase 1 (mite)

Natural Substrates Products

Natural Substrates Products on EC 3.4.22.65 - peptidase 1 (mite)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
CD23 + H2O
?
show the reaction diagram
-
Der p 1 in addition to being highly immunogenic may up-regulate IgE synthesis by virtue of its ability to cleave CD23
-
-
?
lung surfactant protein A + H2O
?
show the reaction diagram
-
degradation of lung surfactant protein A and lung surfactant protein D is associated with diminished binding to carbohydrates and to Dermatophagoides pteronyssinus allergen 1 itself and diminishes capacity to agglutinate bacteria. The degradation and consequent inactivation of lung surfactant protein A and lung surfactant protein D may be a novel mechanism to account for the potent allergenicity of the dust mite allergen
-
-
?
lung surfactant protein D + H2O
?
show the reaction diagram
-
degradation of lung surfactant protein A and lung surfactant protein D is associated with diminished binding to carbohydrates and to Dermatophagoides pteronyssinus allergen 1 itself and diminishes capacity to agglutinate bacteria. The degradation and consequent inactivation of lung surfactant protein A and lung surfactant protein D may be a novel mechanism to account for the potent allergenicity of the dust mite allergen
-
-
?
mas-related G-protein-coupled receptor C11 + H2O
?
show the reaction diagram
mouse protein
-
-
?
mas-related G-protein-coupled receptor X1 + H2O
?
show the reaction diagram
human protein
-
-
?
pro-Der p 3 + H2O
Der p 3 + Der p 3 propeptide
show the reaction diagram
activation
-
-
?
pro-Der p 6 + H2O
Der p 6 + Der p 6 propeptide
show the reaction diagram
activation
-
-
?
pro-Der p 9 + H2O
Der p 9 + Der p 9 propeptide
show the reaction diagram
activation
-
-
?
additional information
?
-