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3.4.22.63: caspase-10

This is an abbreviated version!
For detailed information about caspase-10, go to the full flat file.

Word Map on EC 3.4.22.63

Reaction

strict requirement for Asp at position P1 and has a preferred cleavage sequence of Leu-Gln-Thr-Asp-/-Gly =

Synonyms

apoptotic protease Mch-4, C14.011, CASP10, caspase 10, caspase-10, caspase-10/b, caspase-10beta, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, Mch4

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.63 caspase-10

Inhibitors

Inhibitors on EC 3.4.22.63 - caspase-10

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
acetyl-AEVD-aldehyde
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acetyl-DEVD-aldehyde
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acetyl-IETD-aldehyde
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acetyl-WEHD-aldehyde
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acetyl-YVAD-aldehyde
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benzyloxycarbonyl-AEVD-fluoromethylketone
benzyloxycarbonyl-IETD-fluoromethylketone
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caspase-8/caspase-10 inhibitor
benzyloxycarbonyl-Ile-Glu-Thr-Asp-fluoromethylketone
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benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone
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CBZ-VAD-trifluoromethylketone
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pancaspase inhibitor
cowpox serpin CrmA
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CrmA
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caspase-10 is more resistant than caspase-8, EC 3.4.22.61, to the caspase inhibitor
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DEVD-aldehyde
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DEVD-CHO
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Z-AEVD-fluoromethylketone
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a caspase-10 inhibitor
Z-VAD-fluoromethylketone
additional information
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no inhibition by WEHD-CHO and YVAD-CHO
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