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3.4.22.59: caspase-6

This is an abbreviated version!
For detailed information about caspase-6, go to the full flat file.

Word Map on EC 3.4.22.59

Reaction

strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-/- =

Synonyms

apoptotic protease Mch-2, C14.005, Cas6, Casp-6, Casp.6, Casp6, caspase 6, caspase-6, caspase-6A, caspase-6B, Csp-6, Csp6, HLcaspase-6, MCH2, Pfcasp-6, VEIDase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.59 caspase-6

pH Optimum

pH Optimum on EC 3.4.22.59 - caspase-6

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7 - 7.5
-
reaction with acetyl-VEHD-7-amido-4-methylcoumarin
7.2
-
assay at
additional information
caspase-6 activity is optimal around neutral pH and is almost entirely lost at pH 5.0 and below