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3.4.22.59: caspase-6

This is an abbreviated version!
For detailed information about caspase-6, go to the full flat file.

Word Map on EC 3.4.22.59

Reaction

strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-/- =

Synonyms

apoptotic protease Mch-2, C14.005, Cas6, Casp-6, Casp.6, Casp6, caspase 6, caspase-6, caspase-6A, caspase-6B, Csp-6, Csp6, HLcaspase-6, MCH2, Pfcasp-6, VEIDase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.59 caspase-6

Expression

Expression on EC 3.4.22.59 - caspase-6

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
after the challenges of high temperatures and Aeromonas hydrophila, the transcript expressions of Pfcasp-6 are significantly upregulated in blood and spleen
caspase-6 mRNA levels decrease 3fold in the brains of adult mice exposed to an enriched environment
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caspase-6 mRNA levels increase 2-3fold in the aging mouse cortex and hypothalamus
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in in vitro experiments, the expression of HLcaspase-6 mRNA in coelomocytes is significantly upregulated by lipopolysaccharides or polyriboinosinic-polyribocytidylic acid [poly (I:C)] challenge
staurosporine induces caspase-6
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upregulated in IL-4-induced macrophages