3.4.22.57: caspase-4
This is an abbreviated version!
For detailed information about caspase-4, go to the full flat file.
Word Map on EC 3.4.22.57
-
3.4.22.57
-
inflammasome
-
pyroptosis
-
chop
-
lps
-
caspase-5
-
non-canonical
-
stress-mediated
-
gsdmd
-
glucose-regulated
-
perk
-
stress-associated
-
pyrin
-
gadd153
-
aif
-
salubrinal
-
speck-like
-
atf-6
-
eif2alpha
-
pkr-like
-
gasdermin-d
-
inflammasome-mediated
-
medicine
- 3.4.22.57
- inflammasome
-
pyroptosis
-
chop
- lps
- caspase-5
-
non-canonical
-
stress-mediated
-
gsdmd
-
glucose-regulated
-
perk
-
stress-associated
- pyrin
-
gadd153
- aif
- salubrinal
-
speck-like
- atf-6
- eif2alpha
-
pkr-like
-
gasdermin-d
-
inflammasome-mediated
- medicine
Reaction
strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-/- but also cleaves at Asp-Glu-Val-Asp-/- =
Synonyms
C14.007, Cas4, CASP-4, CASP4, caspase 4, caspase-4, ICE(rel)-II, ICH-2 protease, ICH-3 protease, ICH3 protease, TX, TX protease
ECTree
3.4.22.57 caspase-4Advanced search results
results (
results (Engineering
Engineering on EC 3.4.22.57 - caspase-4
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
additional information
-
knockdown expression of caspase-4 with siRNA in keratinocytes, overexpression of active caspase-4 rescues UVB-induced secretion of IL-1b by caspase-4 knockdown keratinocytes
