3.4.22.55: caspase-2
This is an abbreviated version!
For detailed information about caspase-2, go to the full flat file.
Word Map on EC 3.4.22.55
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3.4.22.55
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caspases
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bcl-2
-
necrosis
-
bid
-
proapoptotic
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anti-apoptotic
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parp
-
raidd
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apoptosis-inducing
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caspase-dependent
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z-vad-fmk
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p53-induced
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tunel
-
jurkat
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polyadp-ribose
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casps
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mitochondria-mediated
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non-apoptotic
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pan-caspase
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apaf-1
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apoptosome
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caspase-mediated
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death-inducing
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cpp32
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fasl
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z-devd-fmk
-
executioner
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xiap
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damage-induced
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etoposide-induced
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anti-fas
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prodomains
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p53-dependent
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trail-induced
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executor
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bh3-only
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ac-devd-cho
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apoptogenic
-
trail-mediated
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procaspase
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caspase-10
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chk1
-
beta-converting
-
mitochondria-dependent
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medicine
-
diagnostics
- 3.4.22.55
-
caspases
- bcl-2
- necrosis
- bid
-
proapoptotic
-
anti-apoptotic
- parp
- raidd
-
apoptosis-inducing
-
caspase-dependent
- z-vad-fmk
-
p53-induced
-
tunel
-
jurkat
-
polyadp-ribose
-
casps
-
mitochondria-mediated
-
non-apoptotic
-
pan-caspase
- apaf-1
- apoptosome
-
caspase-mediated
-
death-inducing
- cpp32
- fasl
- z-devd-fmk
-
executioner
- xiap
-
damage-induced
-
etoposide-induced
-
anti-fas
- prodomains
-
p53-dependent
-
trail-induced
-
executor
-
bh3-only
- ac-devd-cho
-
apoptogenic
-
trail-mediated
-
procaspase
- caspase-10
- chk1
-
beta-converting
-
mitochondria-dependent
- medicine
- diagnostics
Reaction
strict requirement for an Asp residue at P1, with Asp316 being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-/- =
Synonyms
AjCASP, C14.006, CASP-2, Casp2, caspase 2, caspase-2, caspase-2L, caspase-2S, ICH-1, ICH-1 protease, ICH-1L/1S, NEDD-2
ECTree
3.4.22.55 caspase-2Advanced search results
results (
results (Sequence
top
Sequence on EC 3.4.22.55 - caspase-2
Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT 
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). CASP2_HUMAN
452
0
50685
Swiss-Prot
Mitochondrion (Reliability: 5)
CASP2_MOUSE
452
0
50661
Swiss-Prot
Mitochondrion (Reliability: 1)
CASP2_RAT
452
0
50728
Swiss-Prot
Mitochondrion (Reliability: 1)
Q9IB67_XENLA
423
0
47123
TrEMBL
Mitochondrion (Reliability: 5)
A0A6J8E8N6_MYTCO
323
0
36551
TrEMBL
other Location (Reliability: 5)
A0A6J8EBV0_MYTCO
221
0
24860
TrEMBL
other Location (Reliability: 2)
A0A6J8EM18_MYTCO
613
0
69954
TrEMBL
other Location (Reliability: 1)
A0A6J8DVZ2_MYTCO
448
0
51332
TrEMBL
other Location (Reliability: 1)
Q0PKX3_DANRE
435
0
49577
TrEMBL
other Location (Reliability: 4)
A0A6J8A4M0_MYTCO
271
0
31162
TrEMBL
other Location (Reliability: 2)
A0A8B6BZK1_MYTGA
717
0
81973
TrEMBL
other Location (Reliability: 2)
A0A6J8E4X6_MYTCO
420
0
48725
TrEMBL
Mitochondrion (Reliability: 5)
A0A6J8E6Y9_MYTCO
445
0
52053
TrEMBL
other Location (Reliability: 3)
A0A8B6DAG8_MYTGA
613
0
70049
TrEMBL
other Location (Reliability: 1)
A0A6J8EI65_MYTCO
561
0
64175
TrEMBL
other Location (Reliability: 2)
A0A8B6DQI6_MYTGA
418
0
47767
TrEMBL
other Location (Reliability: 2)
A0A8B6BZ93_MYTGA
407
0
46284
TrEMBL
other Location (Reliability: 2)
A0A6J8A0M3_MYTCO
184
0
21081
TrEMBL
other Location (Reliability: 3)
A0A8B6CLY0_MYTGA
407
0
47301
TrEMBL
other Location (Reliability: 4)
A0A6J8BUJ1_MYTCO
735
0
84518
TrEMBL
other Location (Reliability: 1)
A0A8B6HFP6_MYTGA
617
0
69657
TrEMBL
other Location (Reliability: 5)
A0A061IHP9_CRIGR
418
0
46609
TrEMBL
Mitochondrion (Reliability: 1)
A0A6J8EBN6_MYTCO
305
0
34681
TrEMBL
other Location (Reliability: 2)
A0A812BUU6_SEPPH
467
0
53594
TrEMBL
other Location (Reliability: 4)
A0A6J8DM47_MYTCO
404
0
46705
TrEMBL
other Location (Reliability: 3)
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