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3.4.22.44: nuclear-inclusion-a endopeptidase

This is an abbreviated version!
For detailed information about nuclear-inclusion-a endopeptidase, go to the full flat file.

Word Map on EC 3.4.22.44

Reaction

Hydrolyses glutaminyl bonds, and activity is further restricted by preferences for the amino acids in P6 - P1' that vary with the species of potyvirus, e.g. Glu-Xaa-Xaa-Tyr-Xaa-Gln-/-(Ser or Gly) for the enzyme from tobacco etch virus. The natural substrate is the viral polyprotein, but other proteins and oligopeptides containing the appropriate consensus sequence are also cleaved. =

Synonyms

49 kDa proteinase, 49 kDa-Pro, NIA, NIa protease, NIa protein, NIa proteins, NIa-Pro, nuclear inclusion a protease, nuclear inclusion a-protease, nuclear inclusion body protein a, nuclear inclusion protein A protease, nuclear inclusion protein-a protease, nuclear inclusion-a protease, potyviral nuclear inclusion a, potyvirus NIa protease, protease NIa, proteinase Nia, proteinase, polyprotein-processing, Nia, proteins (specific proteins and subclasses), NIa (nuclear inclusion, a), proteins NIa, proteins, small nuclear inclusion NIa, tobacco vein mottling virus protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.44 nuclear-inclusion-a endopeptidase

Posttranslational Modification

Posttranslational Modification on EC 3.4.22.44 - nuclear-inclusion-a endopeptidase

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POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphoprotein
-
the protease activity of NIa-Pro can be modulated by phosphorylation at Ser129