3.4.22.40: bleomycin hydrolase

This is an abbreviated version!
For detailed information about bleomycin hydrolase, go to the full flat file.

Word Map on EC 3.4.22.40

3.4.22.40

luteinizing

paraoxonase

thiolactone

helveticus

peplomycin

lutropins

corneocytes

homocysteinylation

beta-naphthylamide

medicine

hcy-thiolactone

Reaction

Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred =

Synonyms

aminopeptidase C, aminopeptidase H, ApsC, BANA-hydrolase, BH, BH protein, Bleomycin hydrolase, BLH, Blh1p, BLM hydrolase, Blmh, BLMH protein, BMH, citrulline aminopeptidase, Gal6p, Hcy-thiolactonase, homocysteine thiolactonase, HTLase, hydrolase H, More, PEPC, yBLH, yeast cysteine protease

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.40 bleomycin hydrolase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
4	Activating Compound
2648	AA Sequence
9	Application
1	CAS Registry Number
18	Cloned(Commentary)
3	Crystallization (Commentary)
265	Disease/ Diagnostics
3	Expression
6	General Information
1	General Stability
6	IC50 Value
57	Inhibitors
7	kcat/KM [mM/s]
52	KM Value [mM]
15	Localization
1	Metals/Ions
18	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
51	Organism
13	PDB ID
15	pH Optimum
4	pH Range
1	Posttranslational Modification
13	Protein Variants
12	Purification (Commentary)
3	Reaction
1	Reaction Type
51	Reference
56	Source Tissue
9	Specific Activity [micromol/min/mg]
130	Substrates and Products (Substrate)
13	Subunits
44	Synonyms
4	Temperature Optimum [°C]
3	Temperature Stability [°C]
7	Turnover Number [1/s]

Molecular Weight

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Molecular Weight on EC 3.4.22.40 - bleomycin hydrolase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Molecular Weight Search

250000

Oryctolagus cuniculus

gel filtration, PAGE

280000

300000

310000

gel filtration

400000

gel filtration

48000

50000

Oryctolagus cuniculus

5 * 50000, SDS-PAGE

52000

72000

x * 72000, SDS-PAGE and deduced from gene sequence

649347