3.4.22.34: Legumain

This is an abbreviated version!
For detailed information about Legumain, go to the full flat file.

Reaction

hydrolysis of proteins and small molecule substrates at -Asn-/-Xaa- bonds =

Synonyms

AEP, Antigen Sj32, Antigen SM32, As-specific vacuolar cysteine proteinase, Asn-specific vacuolar cysteine proteinase, asparagine endopeptidase, asparaginly endopeptidase, asparaginyl endopepidase, Asparaginyl endopeptidase, asparaginyl endopeptidase legumain, asparaginyl endopeptidase,, asparaginyl proteinase, asparaginyl-specific cysteine endopeptidase, asparagyl-endopeptidase, aspartate-specific endopeptidase, AtLEGgamma, Bean endopeptidase, C197 legumain, c197 Sm32, cysteine protease 1, hemoglobinase, HlLgm, HlLgm2, IrAE, IrAE protein, isae1, isae2, LeG, LEG-1, Leg-2, Leg-4, Leg1, Leg2, Leg3, Leg4, Leg5, legumain, legumain-1, LGMN, lysosomal asparaginycysteine endopeptidase, lysosomal asparaginyl endopeptidase, lysosomal cysteine proteinase, More, N197 legumain, osteoclast inhibitory peptide 2, Ov-aep-1, Phaseolin, Proteinase B, PrVPE1, schistosome legumain, Sj32, Sm32, SmAE, SmAE protein, SPAE, TcLEG3, TcLEG6, TcLEG9, TvAE1, vacuolar processing enzyme, vacuolar processing enzyme 1a, vacuolar processing enzyme 1b, vacuolar processing enzyme 2, vacuolar processing enzyme 3, Vicilin peptidohydrolase, VPE, VPE1a, VPE1b, VPE2, VPE3

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.34 Legumain

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
22	Activating Compound
1004	AA Sequence
6	Application
1	CAS Registry Number
49	Cloned(Commentary)
3	Crystallization (Commentary)
1114	Disease/ Diagnostics
17	Expression
14	General Information
10	General Stability
266	IC50 Value
466	Inhibitors
47	Ki Value [mM]
15	KM Value [mM]
70	Localization
1	Metals/Ions
58	Molecular Weight [Da]
77	Natural Substrates/ Products (Substrates)
124	Organism
61	PDB ID
53	pH Optimum
13	pH Range
7	pH Stability
2	pI Value
48	Posttranslational Modification
16	Protein Variants
39	Purification (Commentary)
7	Reaction
34	Reaction Type
123	Reference
1	Renatured (Commentary)
167	Source Tissue
49	Specific Activity [micromol/min/mg]
3	Storage Stability
324	Substrates and Products (Substrate)
30	Subunits
197	Synonyms
28	Temperature Optimum [°C]
2	Temperature Range [°C]
5	Temperature Stability [°C]
5	Turnover Number [1/s]

Temperature Stability

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Temperature Stability on EC 3.4.22.34 - Legumain

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Temperature Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

26.5

Vigna aconitifolia

-

pH 3.0-7.0, very stable

30313

35

Vigna radiata

-

10 min, stable up to

30308

4 - 10

Saccharum sp.

H2EUL5

the enzyme is less affected when incubated at 4 or 10°C for 1 h

732644

45

Bos taurus

Q95M12

10 min, stable up to

650376

50

Vigna radiata

-

10 min, complete inactivation

30308