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3.4.22.33: Fruit bromelain

This is an abbreviated version!
For detailed information about Fruit bromelain, go to the full flat file.

Word Map on EC 3.4.22.33

Reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Bz-Phe-Val-Arg-/-NHMec is a good synthetic substrate, but there is no action on Z-Arg-Arg-NHMec (c.f. stem bromelain) =

Synonyms

ACMD2_17643, Ananase, Bromelain, bromelain A, bromelain B, Bromelain, juice, Bromelase, Bromelin, EC 3.4.22.4, EC 3.4.22.5, EC 3.4.4.24, Extranase, fastuosain, FBM, Fruit bromelain, Fruit bromelain FA2, Juice bromelain, More, Pinase, Traumanase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.33 Fruit bromelain

Substrates Products

Substrates Products on EC 3.4.22.33 - Fruit bromelain

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
angiotensin II + H2O
hydrolyzed angiotensin II
show the reaction diagram
Azoalbumin + H2O
?
show the reaction diagram
-
-
-
?
azocasein + H2O
?
show the reaction diagram
Benzoyl-Gly-Gly-Lys + H2O
?
show the reaction diagram
-
enzyme form FBA is much more active than FBB
-
-
?
benzoyl-L-arginine ethyl ester + H2O
?
show the reaction diagram
-
artificial substrate
-
-
?
benzoyl-Phe-Val-Arg-4-methylcoumarin 7-amide + H2O
benzoyl-Phe-Val-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
convenient substrate for fruit bromelain, scarcely affected by stem bromelain
-
-
?
benzoyl-Phe-Val-Arg-p-nitroanilide + H2O
benzoyl-Phe-Val-Arg + p-nitroaniline
show the reaction diagram
-
-
-
-
?
benzyl-Phe-Val-Arg-4-nitroanilide + H2O
benzyl-Phe-Val-Arg + 4-nitroaniline
show the reaction diagram
preferred substrate of fruit bromelain
-
-
?
Benzyloxycarbonyl-Ala-Leu + H2O
Benzyloxycarbonyl-Ala + Leu
show the reaction diagram
-
enzyme form FBA is much more active than FBB
-
-
?
benzyloxycarbonyl-Arg-Arg-4-nitroanilide + H2O
benzyloxycarbonyl-Arg-Arg + 4-nitroaniline
show the reaction diagram
-
-
-
?
benzyloxycarbonyl-Arg-Arg-p-nitroanilide + H2O
benzyloxycarbonyl-Arg-Arg + p-nitroaniline
show the reaction diagram
-
-
-
-
?
Benzyloxycarbonyl-Gly-Leu + H2O
Benzyloxycarbonyl-Gly + Leu
show the reaction diagram
-
enzyme form FBA is much more active than FBB
-
-
?
Benzyloxycarbonyl-Gly-Phe + H2O
Benzyloxycarbonyl-Gly + Phe
show the reaction diagram
-
-
-
-
?
Benzyloxycarbonyl-Gly-Tyr + H2O
Benzyloxycarbonyl-Gly + Tyr
show the reaction diagram
-
-
-
-
?
Benzyloxycarbonyl-Gly-Val + H2O
Benzyloxycarbonyl-Gly + Val
show the reaction diagram
-
enzyme form FBA is much more active than FBB
-
-
?
benzyloxyxarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
?
show the reaction diagram
-
-
-
?
bradykinin + H2O
fragments of bradykinin
show the reaction diagram
bromelain + H2O
?
show the reaction diagram
-
rapid self-digestion in aqueous solution, can be prevented by addition of alpha2-macroglobulin
-
?
Carbobenzoxy-Gly-Ala + H2O
Carbobenzoxy-Gly + Ala
show the reaction diagram
-
enzyme form FBA is much more active than FBB
-
-
?
casein + H2O
?
show the reaction diagram
casein + H2O
hydrolyzed casein
show the reaction diagram
-
-
-
-
?
casein + H2O
L-Tyr + ?
show the reaction diagram
-
-
-
-
?
casein + H2O
tyrosine + ?
show the reaction diagram
-
-
-
?
epsilon-NH2-Cap-Ala-Cys(S-Bzl)-7-amido-4-methylcoumarin + H2O
?
show the reaction diagram
-
-
-
?
epsilon-NH2-Cap-Cys(S-Bzl)-Leu-7-amido-4-methylcoumarin + H2O
?
show the reaction diagram
-
-
-
?
epsilon-NH2-Cap-Leu-Cys(S-Bzl)-7-amido-4-methylcoumarin + H2O
?
show the reaction diagram
-
-
-
?
epsilon-NH2-Cap-Leu-Gly-7-amido-4-methylcoumarin + H2O
?
show the reaction diagram
-
-
-
?
epsilon-NH2-Cap-Phe-Arg-7-amido-4-methylcoumarin + H2O
?
show the reaction diagram
-
-
-
?
epsilon-NH2-Cap-Pro-Cys(S-Bzl)-7-amido-4-methylcoumarin + H2O
?
show the reaction diagram
-
-
-
?
Fibrin + H2O
?
show the reaction diagram
Gelatin + H2O
?
show the reaction diagram
Hemoglobin + H2O
?
show the reaction diagram
-
-
-
?
Hemoglobin + H2O
Hydrolyzed hemoglobin
show the reaction diagram
-
-
-
-
?
Isolated soybean protein + H2O
Hydrolyzed soybean protein
show the reaction diagram
-
-
-
-
?
milk protein + H2O
?
show the reaction diagram
N-alpha-benzoyl-DL-arginine-2-naphthylamide + H2O
N-alpha-benzoyl-DL-arginine + 2-naphthylamine
show the reaction diagram
-
-
-
?
N-Benzoyl-L-Arg ethyl ester + H2O
N-Benzoyl-L-Arg + ethanol
show the reaction diagram
-
-
-
-
?
N-benzoyl-L-tyrosine ethyl ester + H2O
?
show the reaction diagram
-
artificial substrate
-
-
?
Nalpha-Benzoyl-Arg amide + H2O
Nalpha-Benzoyl-Arg + NH3
show the reaction diagram
-
-
-
-
?
Nalpha-Benzoyl-DL-Arg 4-nitroanilide + H2O
Nalpha-Benzoyl-DL-Arg + 4-nitroaniline
show the reaction diagram
-
-
-
-
?
Nalpha-benzoyl-L-arginine-4-nitroanilide + H2O
?
show the reaction diagram
-
artificial substrate
-
-
?
ovalbumin + H2O
?
show the reaction diagram
protein + H2O
peptides
show the reaction diagram
-
broad substrate specificity
-
?
sodium caseinate + H2O
?
show the reaction diagram
-
-
-
?
soybean protein + H2O
?
show the reaction diagram
Wheat gluten + H2O
Hydrolyzed wheat gluten
show the reaction diagram
-
-
-
-
?
additional information
?
-