3.4.22.3: ficain
This is an abbreviated version!
For detailed information about ficain, go to the full flat file.
Word Map on EC 3.4.22.3
-
3.4.22.3
-
papain
-
bromelain
-
proteinases
-
cathepsins
-
chymotrypsin
-
ficus
-
cystatins
-
latex
-
alpha-chymotrypsin
-
alloantibody
-
chymopapain
-
phytocystatins
-
active-centre
-
actinidin
-
analysis
-
antiglobulin
-
medicine
-
food industry
-
synthesis
-
2,2\'-dipyridyl
-
industry
- 3.4.22.3
- papain
- bromelain
- proteinases
- cathepsins
- chymotrypsin
- ficus
- cystatins
- latex
- alpha-chymotrypsin
-
alloantibody
- chymopapain
-
phytocystatins
-
active-centre
- actinidin
- analysis
-
antiglobulin
- medicine
- food industry
- synthesis
-
2,2\'-dipyridyl
- industry
Reaction
Similar to that of papain =
Synonyms
debricin, EC 3.4.4.12, ficin, ficin A, ficin B, ficin C, ficin D1, ficin D2, ficin E, ficin S, higueroxyl Delabarre
ECTree
3.4.22.3 ficainAdvanced search results
results (
results (Inhibitors
Inhibitors on EC 3.4.22.3 - ficain
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
amaranth cystatin
Ficus sp.
-
Amaranthus hypochondracus cysteine proteinase inhibitor, GenBank accession number DQ792503
-
methylmethanethiol sulfonate
-
complete inhibition of all five ficin isoforms at 3 mM
Nalpha-tosyl-L-lysine chloromethyl ketone
-
complete inhibition of all five ficin isoforms at 0.1 mM
Nalpha-tosyl-L-phenylalanine chloromethylketone
-
complete inhibition of all five ficin isoforms at 0.1 mM
p-chloromercuribenzoate
-
activity is completely inhibited by the cysteine-group specific inhibitor
Sodium tetrathionate
-
activity is completely inhibited by the cysteine-group specific inhibitor
iodoacetamide
-
activity is completely inhibited, cysteine-group specific inhibitor, confirms the participation of the cysteine residue at the active site of the enzyme
Proflavine
Ficus sp.
-
the inhibitor increases the noncovalent reversible binding affinity of ficin towards the maleimides without affecting the nucleophilic reactivity of the catalytically essential thiol groups which are alkylated in the inactivation reaction
additional information
-
all five ficin isoforms are not inhibited by pepstatin A, Pafabloc SC, and EDTA
-
additional information
-
ficin E is not affected by Mg2+, Ca2+ and Mn2+ at a concentration up to 10 mM. It is unaffected by synthetic (Pefabloc SC, benzamidine) and by natural proteinaceous (aprotinin) serine proteases inhibitors, by aspartic proteases inhibitors (pepstatin A) and by metallo-proteases inhibitors (EDTA, EGTA)
-
