3.4.22.28: picornain 3C

This is an abbreviated version!
For detailed information about picornain 3C, go to the full flat file.

Word Map on EC 3.4.22.28

3.4.22.28

polyproteins

capsid

picornaviruses

non-structural

3c-like

rupintrivir

positive-sense

picornaviridae

rhinoviruses

encephalomyocarditis

enteroviruses

fmdv-specific

noroviruses

vp3

gln-gly

medicine

drug development

shutoff

molecular biology

Reaction

Selective cleavage of Gln-/-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly =

Synonyms

3C protease, 3C protein, 3C proteinase, 3C-like protease, 3C-protease, 3CL, 3cLpro, 3CP, 3Cpro, 3Cpro protease, Avihepatovirus 3C protease, coxsackievirus 3C proteinase, cysteine proteinase 3C, DHAV 3C protease, enterovirus 3C protease, EV71 3Cpro, foot-and-mouth protease 3C, HAC 3C, HAV 3C protease, HAV 3Cpro, hepatitis A virus 3C proteinase, HRV 3C protease, HRV 3Cpro, HRV type-14 3C protease, HRV16 3C protease, Human rhinovirus 3C protease, human rhinovirus type-14 3C protease, nonstructural 3 protease, NS3 protease, NS6 protease, P3C, picornain 3C, picornain-3C, picornaviral 3C protease, picornavirus endopeptidase 3C, poliovirus protease 3C, poliovirus proteinase 3C, protease 3C, proteinase, foot-and-mouth-disease virus, 3C, proteinase, picornavirus, 3C, proteinase, poliovirus, 3C, proteinase, rhinovirus, 3C, rhinovirus 3C protease, rhinovirus protease 3C, SAT-type 3C protease, Senecavirus A 3C protease, SV3CP, SVA 3Cpro, tomato ringspot nepovirus 3C-related protease

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.28 picornain 3C

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
7	Activating Compound
6497	AA Sequence
22	Application
1	CAS Registry Number
80	Cloned(Commentary)
1	Cofactor
22	Crystallization (Commentary)
35	General Information
4	General Stability
154	IC50 Value
492	Inhibitors
18	kcat/KM [mM/s]
24	Ki Value [mM]
40	KM Value [mM]
38	Localization
6	Metals/Ions
19	Molecular Weight [Da]
61	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
182	Organism
450	PDB ID
27	pH Optimum
5	pI Value
1	Posttranslational Modification
120	Protein Variants
54	Purification (Commentary)
1	Reaction
10	Reaction Type
162	Reference
14	Source Tissue
12	Specific Activity [micromol/min/mg]
2	Storage Stability
343	Substrates and Products (Substrate)
8	Subunits
207	Synonyms
25	Temperature Optimum [°C]
2	Temperature Range [°C]
3	Temperature Stability [°C]
36	Turnover Number [1/s]

KI Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KI Value on EC 3.4.22.28 - picornain 3C

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Ki Value Search

0.001903

1-(2-(2-oxo-4-phenyl-2H-chromen-7-yloxy)acetyl)-4-ethylthiosemicarbazide

Hepatovirus A

pH 7.5, 37°C

753494

0.000217

2-(2-oxo-4-phenyl-2H-chromen-7-yloxy)-N'-(1-(4-bromophenyl)ethylidene)acetohydrazide

Hepatovirus A

pH 7.5, 37°C

753494

0.000104

2-(2-oxo-4-phenyl-2H-chromen-7-yloxy)-N'-(1-(4-chlorophenyl)ethylidene)acetohydrazide

Hepatovirus A

pH 7.5, 37°C

753494

0.000042

acetyl-Leu-Ala-Ala-(N,N'-dimethylglutaminal)

Hepatovirus A

25°C, mutant enzyme C24S

648015

0.00004

benzyloxycarbonyl-Leu-Phe-(glutaminol)