3.4.22.26: cancer procoagulant

This is an abbreviated version!
For detailed information about cancer procoagulant, go to the full flat file.

Word Map on EC 3.4.22.26

3.4.22.26

coagulation

proteinase

thromboembolic

clot

thrombosis

intravascular

gordon

amnion-chorion

hypercoagulability

thrombin-antithrombin

thrombogenic

three-stage

prothrombotic

warfarin

benson

anti-cp

k-dependent

haemostatic

x-activating

medicine

Reaction

specific cleavage of Arg-/-Ile bond in Factor X to form Factor Xa =

Synonyms

cancer procoagulant, CP

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.26 cancer procoagulant

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Results	in table
11	Activating Compound
2	Application
1	CAS Registry Number
513	Disease/ Diagnostics
1	Expression
6	General Information
6	General Stability
1	IC50 Value
90	Inhibitors
5	kcat/KM [mM/s]
1	Ki Value [mM]
11	KM Value [mM]
7	Localization
32	Metals/Ions
6	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
24	Organism
2	Oxidation Stability
7	pH Optimum
1	pI Value
6	Posttranslational Modification
11	Purification (Commentary)
1	Reaction
6	Reaction Type
24	Reference
62	Source Tissue
32	Specific Activity [micromol/min/mg]
1	Storage Stability
97	Substrates and Products (Substrate)
5	Subunits
14	Synonyms
6	Temperature Optimum [°C]
10	Turnover Number [1/s]

KM Value

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KM Value on EC 3.4.22.26 - cancer procoagulant

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0.109

D-Ala-Pro-Arg-4-nitroanilide

Homo sapiens

pH 7.2

653983

0.027

D-Ile-Pro-Arg-4-nitroanilide

Homo sapiens

pH 7.2

653983

0.306

Glu-Glu-Pro-Arg-4-nitroanilide

Homo sapiens

pH 7.2

653983

0.3933

LPAPR-7-amido-4-methylcoumarin

Homo sapiens

pH 7.4, 37°C

755322

0.061

N-p-tosyl-Gly-Pro-Arg-4-nitroanilide

Homo sapiens

pH 7.2

653983

0.153

N-p-tosyl-Gly-Pro-Lys-4-nitroanilide

Homo sapiens

pH 7.2

653983

0.2265

PQVR-7-amido-4-methylcoumarin

Homo sapiens

pH 7.4, 37°C

755322

0.3463

QSPVR-7-amido-4-methylcoumarin

Homo sapiens

pH 7.4, 37°C

755322

0.2675

QVR-7-amido-4-methylcoumarin

Homo sapiens

pH 7.4, 37°C

755322

0.01182

tert-benzyloxycarbonyl-QVR-7-amido-4-methylcoumarin

Homo sapiens

pH 7.4, 37°C

755322

additional information

Rattus norvegicus

Michaelis-Menten kinetics, Km calculated using different plots, kinetic analysis, overview

755327