Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.22.26: cancer procoagulant

This is an abbreviated version!
For detailed information about cancer procoagulant, go to the full flat file.

Word Map on EC 3.4.22.26

Reaction

specific cleavage of Arg-/-Ile bond in Factor X to form Factor Xa =

Synonyms

cancer procoagulant, CP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.26 cancer procoagulant

Inhibitors

Inhibitors on EC 3.4.22.26 - cancer procoagulant

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(D)-Phe-Pro-(D,L)-(4'-guanidino)-Phe-trifluoromethyl ketone
-
-
(D)-Phe-Pro-(D,L)-Lys-trifluoromethyl ketone
-
weak
(D)-Phe-Pro-Arg-chloromethyl ketone
-
-
(NH4)2SO4
-
76% inhibition at about 40 mM
2-Vinylpyridine
-
-
alpha1-Aantichymotrypsin
-
alpha2-Macroglobulin
-
antiCP polyclonal antibody
-
-
-
antiFVIIa polyclonal antibody
-
-
-
antipain
benzamidine
-
strong inhibition
benzoxycarbonyl-Lys-CHN2
-
-
CaCl2
-
91% inhibition at about 40 mM
diisopropylfluorophosphate
E-64
-
-
EDTA
-
low inhibition
Hg2+
-
0.1 mM: 85.5% decrease of activity
HgCl2
iodoacetamide
leupeptin
Mercuric chloride
MgCl2
-
81% inhibition at about 40 mM
MgSO4
-
68% inhibition at about 40 mM
Mn2+
-
above 1 mM, activates below 1 mM
N-benzyloxycarbonyl-Phe-Ala-CHN2
-
-
NaCl
-
12-21% inhibition, respectively
p-chloromercuric benzoate
-
-
pepstatin A
-
low inhibition
Peptidyl chloromethanes
Peptidyl diazomethanes
Peptidyl diazomethyl ketones
Peptidyl dimethylsulfonium salts
-
Peptidyl sulfonium salts
-
-
-
phenylmethylsulfonyl fluoride
Phenylmethylsulfonylfluoride
-
strong inhibition
trans-epoxysuccinyl-L-leucyl-amido(4-guanidino)butane
trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane
additional information
-