3.4.22.2: papain

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For detailed information about papain, go to the full flat file.

Word Map on EC 3.4.22.2

3.4.22.2

cathepsins

proteinases

chymotrypsin

pepsin

cystatins

bromelain

igg

hydrolysates

cartilage

immunoglobulin

ficin

pronase

proteoglycans

erythrocyte

glycosaminoglycans

alpha-chymotrypsin

elastase

neuraminidase

chondroitin

alcalase

subtilisin

latex

thermolysin

carica

allergen

articular

agglutination

collagenase

emphysema

plasmin

kininogens

fab\'2

anti-d

intra-articular

bacteriocins

pineapple

legumains

l-like

pancreatin

meromyosin

dermatan

emphysematous

chondroitinase

antiglobulin

nutrition

actin-activated

medicine

food industry

enzyme-treated

industry

alloantibody

subfragment-1

analysis

synthesis

carlsberg

biotechnology

procathepsins

Reaction

Hydrolysis of proteins with broad specificity for peptide bonds, but preference for an amino acid bearing a large hydrophobic side chain at the P2 position. Does not accept Val in P1' =

Synonyms

Adolph's Meat Tenderizer, arbuz, CpXCP5, EC 3.4.4.10, enzeco papain, papain, papain-like cysteine protease, papain-like protease, papaine, papaya peptidase I, papaya proteinase 1, Papaya proteinase I, papayotin, PLCP, PLpro, PPI, summetrin, velardon

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.2 papain

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Results	in table
13	Activating Compound
56	AA Sequence
37	Application
1	CAS Registry Number
6	Cloned(Commentary)
17	Crystallization (Commentary)
4	General Information
16	General Stability
3	IC50 Value
106	Inhibitors
10	kcat/KM [mM/s]
17	Ki Value [mM]
80	KM Value [mM]
4	Localization
3	Metals/Ions
10	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
9	Organic Solvent Stability
144	Organism
40	PDB ID
44	pH Optimum
10	pH Range
15	pH Stability
1	pI Value
6	Posttranslational Modification
7	Protein Variants
19	Purification (Commentary)
2	Reaction
11	Reaction Type
143	Reference
3	Renatured (Commentary)
48	Source Tissue
16	Specific Activity [micromol/min/mg]
9	Storage Stability
190	Substrates and Products (Substrate)
6	Subunits
35	Synonyms
42	Temperature Optimum [°C]
11	Temperature Range [°C]
50	Temperature Stability [°C]
53	Turnover Number [1/s]

Reaction Type

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Reaction Type on EC 3.4.22.2 - papain

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acyl transfer

hydrolysis

hydrolysis of peptide bond

3 entries

polymerization

Carica papaya

678470