3.4.22.16: cathepsin H
This is an abbreviated version!
For detailed information about cathepsin H, go to the full flat file.
Word Map on EC 3.4.22.16
Reaction
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-/- bonds) as well as an endopeptidase =
Synonyms
aleurain, aleuron thiol protease, alpha-N-benzoyl-arginine 2-naphthylamide hydrolase, alpha-N-benzoylarginine-beta-naphthylamide hydrolase, Cat H, CatB3, CatH, cathepsin B3, cathepsin Ba, cathepsin H, cathepsin H-like cysteine proteinase, CTSH, procathepsin H
ECTree
3.4.22.16 cathepsin HAdvanced search results
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results (Crystallization
Crystallization on EC 3.4.22.16 - cathepsin H
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CRYSTALLIZATION (Commentary) 
ORGANISM
UNIPROT
LITERATURE
comparison of structure and primary sequences of 5 papain, actinidin, cathepsins B and H and stem bromelain yields high degree of similarity
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purified wild-type and C26S mutant procathepsin H, sitting drop vapor diffusion method, 5.7 mg/ml protein, crystal growth from 0.1 M Na2HPO4/citric acid, pH 4.2, and 2.0 M (NH4)2SO4, 1 week, 20°C, method optimization, X-ray diffraction structure determination and analysis at 2.0 A and 1.66 A resolution, respectively, molecular replacement and modeling
general and secondary structure, structure of active-site cleft, mechanistic conclusions drawn from crystallographic study, mini-chain attached to active-site cleft of enzyme body via disulfide bond, structural comparison reveals high similarity to actinidin
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