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3.4.22.16: cathepsin H

This is an abbreviated version!
For detailed information about cathepsin H, go to the full flat file.

Word Map on EC 3.4.22.16

Reaction

Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-/- bonds) as well as an endopeptidase =

Synonyms

aleurain, aleuron thiol protease, alpha-N-benzoyl-arginine 2-naphthylamide hydrolase, alpha-N-benzoylarginine-beta-naphthylamide hydrolase, Cat H, CatB3, CatH, cathepsin B3, cathepsin Ba, cathepsin H, cathepsin H-like cysteine proteinase, CTSH, procathepsin H

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.16 cathepsin H

Cloned

Cloned on EC 3.4.22.16 - cathepsin H

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
closely related to rat cathepsin H
-
expressed in Pichia pastoris
gene CTSH, real-time PCR enzyme expression analysis in skin and keratinocyte culture
procathepsin H (Ala1P-Val220) construct is cloned with an N-terminal gp64 secretion signal peptide and an uncleavable C-terminal His6-tag, recombinant expression of wild-type enzyme in Spodoptera frugiperda Sf9 cells using the baculovirus transfection system, recombinant expression of His-tagged mutant enzymes in HEK-293T cells using the lentiviral viral vector CD731B
sequence comparison between rat and human gene and protein
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