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3.4.21.B50: DegQ peptidase

This is an abbreviated version!
For detailed information about DegQ peptidase, go to the full flat file.

Reaction

Synonyms

B3234, DEG2, Deg2 protease, DegQ, DegQVh, HhoA peptidase, S01.274, S01.482

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B50 DegQ peptidase

General Information

General Information on EC 3.4.21.B50 - DegQ peptidase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
physiological function
additional information
The Deg2 protease domain consists of a catalytic triad comprising His159, Asp190, and Ser268. The enzyme contains a unique second PDZ domain (PDZ2) following a conventional PDZ domain (PDZ1), with PDZ2 orchestrating the cage assembly of the enzyme, a conserved internal ligand for PDZ2 mediates hexamer formation and locks the protease in the resting state