Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.21.B5: mast cell protease 5

This is an abbreviated version!
For detailed information about mast cell protease 5, go to the full flat file.

Word Map on EC 3.4.21.B5

Reaction

endoprotease activity =

Synonyms

alpha-chymase, chymase1, chymase2, mast cell chymases 5, mast cell protease-5, MCP-5, MMCP-5, MMCP-5', rat mast cell protease 5, rMCP-5, S01.150

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B5 mast cell protease 5

Reference

Reference on EC 3.4.21.B5 - mast cell protease 5

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chu, W.; Johnson, D.A.; Musich, P.R.
Molecular cloning and characterization of mouse mast cell chymases
Biochim. Biophys. Acta
1121
83-87
1992
Mus musculus (P21844), Mus musculus (Q8VDE7)
Manually annotated by BRENDA team
Huang, R.Y.; Blom, T.; Hellman, L.
Cloning and structural analysis of MMCP-1, MMCP-4 and MMCP-5, three mouse mast cell-specific serine proteases
Eur. J. Immunol.
21
1611-1621
1991
Mus musculus
Manually annotated by BRENDA team
McNeil, H.P.; Austen, K.F.; Somerville, L.L.; Gurish, M.F.; Stevens, R.L.
Molecular cloning of the mouse mast cell protease-5 gene. A novel secretory granule protease expressed early in the differentiation of serosal mast cells
J. Biol. Chem.
266
20316-20322
1991
Mus musculus (P21844), Mus musculus
Manually annotated by BRENDA team
Karlson, U.; Pejler, G.; Tomasini-Johansson, B.; Hellman, L.
Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity
J. Biol. Chem.
278
39625-39631
2003
Rattus norvegicus (P50339)
Manually annotated by BRENDA team
Reynolds, D.S.; Stevens, R.L.; Lane, W.S.; Carr, M.H.; Austen, K.F.; Serafin, W.E.
Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases
Proc. Natl. Acad. Sci. USA
87
3230-3234
1990
Mus musculus
Manually annotated by BRENDA team
Abonia, J.P.; Friend, D.S.; Austen, W.G.; Moore, F.D.; Carroll, M.C.; Chan, R.; Afnan, J.; Humbles, A.; Gerard, C.; Knight, P.; Kanaoka, Y.; Yasuda, S.; Morokawa, N.; Austen, K.F.; Stevens, R.L.; Gurish, M.F.
Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle
J. Immunol.
174
7285-7291
2005
Mus musculus
Manually annotated by BRENDA team
De Filippis, D.; Russo, A.; DAmico, A.; Esposito, G.; Pietropaolo, C.; Concetta, P.; Cinelli, M.; Russo, G.; Iuvone, T.
Cannabinoids reduce granuloma-associated angiogenesis in rats by controlling transcription and expression of mast cell protease-5
Br. J. Pharmacol.
154
1672-1679
2008
Rattus norvegicus
Manually annotated by BRENDA team
Simard, E.; Jin, D.; Takai, S.; Miyazaki, M.; Brochu, I.; DOrleans-Juste, P.
Chymase-dependent conversion of Big endothelin-1 in the mouse in vivo
J. Pharmacol. Exp. Ther.
328
540-548
2009
Mus musculus
Manually annotated by BRENDA team
De Filippis, D.; Russo, A.; De Stefano, D.; Cipriano, M.; Esposito, D.; Grassia, G.; Carnuccio, R.; Russo, G.; Iuvone, T.
Palmitoylethanolamide inhibits rMCP-5 expression by regulating MITF activation in rat chronic granulomatous inflammation
Eur. J. Pharmacol.
725
64-69
2014
Rattus norvegicus
Manually annotated by BRENDA team
Stevens, R.L.; McNeil, H.P.; Wensing, L.A.; Shin, K.; Wong, G.W.; Hansbro, P.M.; Krilis, S.A.
Experimental arthritis is dependent on mouse mast cell protease-5
J. Biol. Chem.
292
5392-5404
2017
Mus musculus (P21844), Mus musculus
Manually annotated by BRENDA team