3.4.21.B45: kallikrein 14
This is an abbreviated version!
For detailed information about kallikrein 14, go to the full flat file.
Word Map on EC 3.4.21.B45
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3.4.21.B45
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klk5
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stratum
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desquamation
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corneum
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netherton
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proteinase-activated
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trypsin-like
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kazal-type
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lekti
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corneodesmosomes
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medicine
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kazal
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granulosum
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endocrine-related
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spink6
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diagnostics
- 3.4.21.B45
- klk5
-
stratum
-
desquamation
- corneum
- netherton
-
proteinase-activated
-
trypsin-like
-
kazal-type
- lekti
-
corneodesmosomes
- medicine
-
kazal
-
granulosum
-
endocrine-related
- spink6
- diagnostics
Reaction
proteolytic cleavage of polypeptides =
Synonyms
hK 14, hK14, kallikrein 14, kallikrein-related peptidase 14, KLK14, S01.029, SCTE
ECTree
3.4.21.B45 kallikrein 14Advanced search results
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APPLICATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
diagnostics
mRNA overexpression of kallikrein 14 is an independent predictor of poor overall survival in chronic lymphocytic leukemia patients
medicine
medicine
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KLK14 has the prognostic potential to recognize prostate cancer patients at higher risk of disease recurrence after radical prostatectomy. As an independent factor, KLK14 is expected to supplement postoperative prostate-specific antigen values for a more precise prognosis
medicine
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normal salivary glands, pleomorphic adenoma, adenoid cystic carcinoma and mucoepidermoid carcinoma show strong expression of KLK14 in ductal and non-ductal cells. Both pleomorphic adenoma and adenoid cystic carcinoma show higher KLK14 levels than normal glands and mucoepidermoid carcinoma tissues. There are no statistically significant associations between levels of KLK14 and clinical parameters
medicine
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study on the clinical value of seminal kallikreins in the evaluation of semen quality and differential diagnosis and etiology of abnormal liquefaction and/or viscosity. Combination of KLK2, 3, 13, and 14 and KLK1, 2, 5, 6, 7, 8, 10, 13, and 14 shows very strong discriminatory potential for semen liquefaction and viscosity, respectively. Liquefaction state is associated with several parameters of sperm motility. KLK14 is differentially expressed in asthenospermic cases
medicine
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KLK14 and its receptor proteinase-activated receptor-2 represent therapeutic targets for colon tumorigenesis
