3.4.21.B39: stratum corneum tryptic enzyme

This is an abbreviated version!
For detailed information about stratum corneum tryptic enzyme, go to the full flat file.

Reaction

proteolytic cleavage of polypeptides =

Synonyms

GK-5, hK5, HSC tryptic enzyme, human kallikrein 5, human stratum corneum trypsin-like enzyme, human tissue kallikrein 5, K5, kallikrein 5, kallikrein protein 5, kallikrein-5, kallikrein-like protein 2, kallikrein-related peptidase 5, KLK-L2, KLK5, More, S01.017, SCTE, strateum-corneum trypsin-like serine protease, stratum corneum tryptic enzyme, tissue kallikrein, tissue kallikrein 5

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B39 stratum corneum tryptic enzyme

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
7	Activating Compound
3	AA Sequence
6	Application
2	CAS Registry Number
13	Cloned(Commentary)
3	Crystallization (Commentary)
237	Disease/ Diagnostics
6	Expression
11	General Information
8	IC50 Value
51	Inhibitors
1	kcat/KM [mM/s]
17	Ki Value [mM]
20	KM Value [mM]
3	Localization
8	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
43	Organism
6	pH Optimum
1	pH Range
6	Posttranslational Modification
1	Protein Variants
8	Purification (Commentary)
6	Reaction
8	Reaction Type
41	Reference
105	Source Tissue
1	Storage Stability
98	Substrates and Products (Substrate)
2	Subunits
72	Synonyms
3	Temperature Optimum [°C]
18	Turnover Number [1/s]

IC50 Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

IC50 Value on EC 3.4.21.B39 - stratum corneum tryptic enzyme

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to IC50 Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.000122

(S)-methyl-1-((3'S,4'S)-4'-(tert-butoxycarbonylamino)-3'-hydroxy-5'-phenylpentanoyl) pyrrolidine-2-carboxylate

Homo sapiens

Q9Y337

pH 7.5, 37°C

753482

0.000115

(S)-methyl-2-((3'S,4'S)-4'-(tert-butoxycarbonylamino)-3'-hydroxy-5'-phenylpentanamido)-3-methylbutanoate

Homo sapiens

Q9Y337

pH 7.5, 37°C

753482

0.000112

(S)-methyl-2-((3'S,4'S)-4'-(tert-butoxycarbonylamino)-3'-hydroxy-5'-phenylpentanamido)-3-phenylpropanoate

Homo sapiens

Q9Y337

pH 7.5, 37°C

753482

0.0729

8,8'-paepalantine dimer

Homo sapiens

-

pH and temperature not specified in the publication

717354

0.0125

fukugetin

Homo sapiens

-

at pH 7.5 and 37°C

752984

0.3674

paepalantine

Homo sapiens

-

pH and temperature not specified in the publication

717354

0.0537

vioxanthin

Homo sapiens

-

pH and temperature not specified in the publication

717354

0.009

Zn2+

Homo sapiens

Q9Y337

in 150 mM NaCl, 20 mM HEPES, 0.04 mM imidazole, 0.005% (v/v) Tween 20, at pH 7.0

681454