3.4.21.B39: stratum corneum tryptic enzyme
This is an abbreviated version!
For detailed information about stratum corneum tryptic enzyme, go to the full flat file.
Word Map on EC 3.4.21.B39
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3.4.21.B39
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klk5
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keratinocytes
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desquamation
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cathelicidin
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netherton
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spink5
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rosacea
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kazal-type
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lekti
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filaggrin
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lympho-epithelial
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corneodesmosomes
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transepidermal
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lymphopoietin
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corneodesmosin
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kazal
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desmocollin
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corneocyte
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medicine
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diagnostics
- 3.4.21.B39
- klk5
- keratinocytes
-
desquamation
- cathelicidin
- netherton
-
spink5
- rosacea
-
kazal-type
- lekti
- filaggrin
-
lympho-epithelial
-
corneodesmosomes
-
transepidermal
- lymphopoietin
- corneodesmosin
-
kazal
-
desmocollin
-
corneocyte
- medicine
- diagnostics
Reaction
proteolytic cleavage of polypeptides =
Synonyms
GK-5, hK5, HSC tryptic enzyme, human kallikrein 5, human stratum corneum trypsin-like enzyme, human tissue kallikrein 5, K5, kallikrein 5, kallikrein protein 5, kallikrein-5, kallikrein-like protein 2, kallikrein-related peptidase 5, KLK-L2, KLK5, More, S01.017, SCTE, strateum-corneum trypsin-like serine protease, stratum corneum tryptic enzyme, tissue kallikrein, tissue kallikrein 5
ECTree
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Application
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diagnostics
medicine
diagnostics
KLK5 is a promising biomarker for prostate cancer diagnosis and prognosis
diagnostics
the expression level of human kallikrein 5 in tumor stromal cells is a promising biomarker for poor prognosis in triple-negative breast cancer. Patients with high histological grade are more prone to distal metastasis and aggressive tumor progression
regulation by protease inhibitors may have potential clinical applications
medicine
KLK5 mRNA, analyzed by quantitative PCR in prostate needle biopsies, could be an independent biomarker for the differential diagnosis and prognosis in prostate cancer
medicine
human kallikrein 5 is a potential target for the treatment of skin inflammation and cancer