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3.4.21.B30: UmuD protein

This is an abbreviated version!
For detailed information about UmuD protein, go to the full flat file.

Word Map on EC 3.4.21.B30

Reaction

involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template =

Synonyms

DNA damage response protein, error-prone polymerase accessory, ImpA, MucA, polymerase manager protein UmuD, RulA, S24.003, SamA, UmuD, UmuD', UmuD2, UmuDAb, UmuDC, umuDpR, UmuDpR protein, UmuD’2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B30 UmuD protein

Expression

Expression on EC 3.4.21.B30 - UmuD protein

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
cellular level of UmuD increases approximately 10fold upon SOS induction
-
the enzyme is expressed shortly after the induction of the SOS response
the mutant two complete umuDC operons (A1S_0636-A1S_0637 and A1S_1174-A1S_1173) and one unlinked umuD homolog (A1S_1389) determined in strain ATCC 17978 are induced by DNA damage and Rif
UmuD2 is up-regulated as part of the SOS response