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3.4.21.B30: UmuD protein

This is an abbreviated version!
For detailed information about UmuD protein, go to the full flat file.

Word Map on EC 3.4.21.B30

Reaction

involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template =

Synonyms

DNA damage response protein, error-prone polymerase accessory, ImpA, MucA, polymerase manager protein UmuD, RulA, S24.003, SamA, UmuD, UmuD', UmuD2, UmuDAb, UmuDC, umuDpR, UmuDpR protein, UmuD’2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B30 UmuD protein

Cloned

Cloned on EC 3.4.21.B30 - UmuD protein

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21(DE3) cells
expression in Escherichia coli
fusion protein with beta-galactosidase
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gene umuD
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gene umuD, recombinant expression of wild-type and mutant enzymes in Escherichia coli strain BL21 (DE3)
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gene umuDAb, the umuD homologue umuDAb is present throughout the Acinetobacter genus and encodes an extra N-terminal region, transformation of Escherichia coli wild-type strain AB1157 and mutant cells with plasmids bearing various umuDAb alleles. UmuD is not required for UmuDAb expression from its native promoter, nor its disappearance after DNA damage through intermolecular interactions with Escherichia coli UmuD
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wild-type and mutant lacking the N-terminal extension
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