3.4.21.B27: proprotein convertase 7
This is an abbreviated version!
For detailed information about proprotein convertase 7, go to the full flat file.
Word Map on EC 3.4.21.B27
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3.4.21.B27
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furin
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tmprss6
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endoproteases
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pcsks
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medicine
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pafah1b2
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hemochromatosis
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furin-like
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pnpla3
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mbtps1
- 3.4.21.B27
- furin
- tmprss6
- endoproteases
-
pcsks
- medicine
- pafah1b2
- hemochromatosis
-
furin-like
-
pnpla3
-
mbtps1
Reaction
cleaves proteins typically at sites marked by the consensus Arg-Xaa-(Lys/Arg)-Arg sequence =
Synonyms
furin, LPC, lymphoma PC, PC-7, PC7, PC7A, PC7B, PCSK7, Proprotein convertase, proprotein convertase 7, proprotein convertase PCSK7, proprotein convertase subtilisin/kexin type 7, rPC7, S08.077, SPC7, subtilisin-like proprotein convertase 7
ECTree
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Source Tissue
Source Tissue on EC 3.4.21.B27 - proprotein convertase 7
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correlation between plasma levels of the soluble human transferrin receptor 1 and the PCSK7 gene
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the cleaved form of PC7 is present in both embryos and oocytes, PC7-like activity is not detected in oocytes
additional information
expression of gene SPC7 mRNA in Xenopus laevis embryos at different developmental stages by real-time PCR expression analysis, overview
the enzyme is ubiquitously expressed and evident already during the early development, enzyme expression during the first week of fish development and in several tissues, overview
additional information
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the enzyme is ubiquitously expressed and evident already during the early development, enzyme expression during the first week of fish development and in several tissues, overview
additional information
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enzyme is expressed in a broad range of tissues and cell lines
additional information
no mRNA transcripts in liver, kidney, heart and spleen
additional information
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present in Chief cell granules but not in endocrine cells