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3.4.21.B27: proprotein convertase 7

This is an abbreviated version!
For detailed information about proprotein convertase 7, go to the full flat file.

Word Map on EC 3.4.21.B27

Reaction

cleaves proteins typically at sites marked by the consensus Arg-Xaa-(Lys/Arg)-Arg sequence =

Synonyms

furin, LPC, lymphoma PC, PC-7, PC7, PC7A, PC7B, PCSK7, Proprotein convertase, proprotein convertase 7, proprotein convertase PCSK7, proprotein convertase subtilisin/kexin type 7, rPC7, S08.077, SPC7, subtilisin-like proprotein convertase 7

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B27 proprotein convertase 7

Source Tissue

Source Tissue on EC 3.4.21.B27 - proprotein convertase 7

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
correlation between plasma levels of the soluble human transferrin receptor 1 and the PCSK7 gene
Manually annotated by BRENDA team
-
expression is restricted to non-cancerous HOSE cell lines
Manually annotated by BRENDA team
-
T-lymphocyte including CD4+ cells
Manually annotated by BRENDA team
-
the cleaved form of PC7 is present in both embryos and oocytes, PC7-like activity is not detected in oocytes
Manually annotated by BRENDA team
additional information