3.4.21.B26: proprotein convertase 5

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For detailed information about proprotein convertase 5, go to the full flat file.

Word Map on EC 3.4.21.B26

3.4.21.B26

furin

subtilisin-like

medicine

endoproteases

pcsks

furin-like

Reaction

cleavage at the RX(K/R)R consensus motif. Release of mature proteins from their proproteins by cleavage of Arg-Xaa-Yaa-Arg-/-Zaa bonds, where Xaa can be any amino acid and Yaa is Arg or Lys. =

Synonyms

convertase PC5/6, PC5, PC5-A, PC5-B, PC5/6, PC5/6A, PC5/6B, PC5A, PC5B, PC6, PCSK5, prohormone convertase 5, prohormone convertase 5/6, proprotein convertase 5/6, proprotein convertase 5/6A, proprotein convertase PC5/6, proprotein convertase subtilisin/kexin type 5, S08.076, subtilisin/kexin type 5

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.B26 proprotein convertase 5

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Results	in table
2	Activating Compound
3	AA Sequence
8	Application
1	CAS Registry Number
9	Cloned(Commentary)
88	Disease/ Diagnostics
3	Expression
19	General Information
26	Inhibitors
8	Ki Value [mM]
7	KM Value [mM]
16	Localization
2	Metals/Ions
10	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
36	Organism
1	Posttranslational Modification
3	Protein Variants
4	Purification (Commentary)
1	Reaction
6	Reaction Type
36	Reference
118	Source Tissue
37	Substrates and Products (Substrate)
66	Synonyms

Synonyms

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Synonyms on EC 3.4.21.B26 - proprotein convertase 5

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convertase PC5/6

PC5

PC5-A

PC5-B

PC5/6

PC5/6A

PC5/6B

proprotein convertase 5/6 (PC5/6) has two splice variants: soluble PC5/6A and membrane-bound PC5/6B

PC5A

PC5B

PC6

PCSK5

prohormone convertase 5

Mus musculus

Q04592

682249

prohormone convertase 5/6

Mus musculus

Q04592

678042

proprotein convertase 5/6

3 entries

proprotein convertase 5/6A

Homo sapiens

Q92824

731111, 752449

proprotein convertase PC5/6

2 entries

proprotein convertase subtilisin/kexin type 5

UniProt

S08.076

Merops ID

subtilisin/kexin type 5

Homo sapiens

717191