3.4.21.B25: PACE4 proprotein convertase

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For detailed information about PACE4 proprotein convertase, go to the full flat file.

Reaction

releases mature proteins from their proproteins by cleavage of Arg-Xaa-Yaa-Arg-Zaa bonds, where Xaa can be any amino acid and Yaa is Arg or Lys =

Synonyms

PACE 4, PACE-4, PACE4, PACE4/SPC4, paired basic amino acid cleaving enzyme 4, paired basic amino acid-cleaving enzyme 4, paired basic amino-acid-cleaving enzyme-4, PC7, proprotein convertase PACE4, S08.075, SPC4, subtilisin-like proprotein convertase, subtilisin-like proprotein convertase 4, subtilisin-like proprotein convertase PACE4, XPACE4

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B25 PACE4 proprotein convertase

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Results	in table
4	Activating Compound
7	AA Sequence
13	Application
1	CAS Registry Number
24	Cloned(Commentary)
425	Disease/ Diagnostics
7	Expression
19	General Information
30	IC50 Value
78	Inhibitors
46	Ki Value [mM]
2	KM Value [mM]
7	Localization
2	Metals/Ions
18	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
53	Organism
1	pH Optimum
5	Posttranslational Modification
7	Protein Variants
1	Reaction
30	Reaction Type
52	Reference
75	Source Tissue
53	Substrates and Products (Substrate)
2	Subunits
70	Synonyms
1	Temperature Optimum [°C]
1	Temperature Range [°C]

Temperature Optimum

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Temperature Optimum on EC 3.4.21.B25 - PACE4 proprotein convertase

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TEMPERATURE OPTIMUM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

37

Homo sapiens

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