3.4.21.B25: PACE4 proprotein convertase
This is an abbreviated version!
For detailed information about PACE4 proprotein convertase, go to the full flat file.
Word Map on EC 3.4.21.B25
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3.4.21.B25
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convertases
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furin
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prohormone
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endoproteases
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furin-deficient
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furin-like
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alpha1-pdx
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dibasic
-
pro-proteins
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alpha1-antitrypsin
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portland
-
endoproteolysis
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diagnostics
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kexin
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kexin-like
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ski-1
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cys-rich
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medicine
-
subtilisin-related
- 3.4.21.B25
-
convertases
- furin
-
prohormone
- endoproteases
-
furin-deficient
-
furin-like
- alpha1-pdx
-
dibasic
-
pro-proteins
- alpha1-antitrypsin
- portland
-
endoproteolysis
- diagnostics
- kexin
-
kexin-like
- ski-1
-
cys-rich
- medicine
-
subtilisin-related
Reaction
releases mature proteins from their proproteins by cleavage of Arg-Xaa-Yaa-Arg-Zaa bonds, where Xaa can be any amino acid and Yaa is Arg or Lys =
Synonyms
PACE 4, PACE-4, PACE4, PACE4/SPC4, paired basic amino acid cleaving enzyme 4, paired basic amino acid-cleaving enzyme 4, paired basic amino-acid-cleaving enzyme-4, PC7, proprotein convertase PACE4, S08.075, SPC4, subtilisin-like proprotein convertase, subtilisin-like proprotein convertase 4, subtilisin-like proprotein convertase PACE4, XPACE4
ECTree
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KI Value
KI Value on EC 3.4.21.B25 - PACE4 proprotein convertase
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0.012
2-(11-hydroxy-3-oxo-3H-dibenzo[c,h]xanthen-7-yl)benzoic acid
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0.0083
3,3',3'',3'''-(benzene-1,4-diyldimethanetriyl)tetrakis(4-hydroxy-2H-chromen-2-one)
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0.014
3,3'-(1,3-benzodioxol-5-ylmethanediyl)bis(4-hydroxy-2H-chromen-2-one)
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0.013
3,3'-(2,3-dihydro-1H-inden-5-ylmethanediyl)bis(4-hydroxy-2H-chromen-2-one)
-
0.00011
Ac-LLLLR-((2S)-amino-3S-guanidinobutyryl)-KR-NH2
pH and temperature not specified in the publication
0.00051
Ac-LLLLR-((2S,3R)-diaminobutyryl)-KR-NH2
pH and temperature not specified in the publication
0.00027
Ac-LLLLR-((2S,3S)-diaminobutyryl)-KR-NH2
pH and temperature not specified in the publication
0.00066
Ac-LLLLR-(2,3-diaminobutyryl)-KR-NH2
pH and temperature not specified in the publication
0.00216
Ac-LLLLR-(2,3-diaminopropionyl)-KR-NH2
pH and temperature not specified in the publication
0.00055
Ac-LLLLR-(2-amino-3-guanidinopropionyl)-KR-NH2
pH and temperature not specified in the publication
0.000087
Ac-LLLLR-(2-amino-4-guanidinobutyryl)-KR-NH2
pH and temperature not specified in the publication
0.000105
Ac-LLLLR-Orn-KR-NH2
pH and temperature not specified in the publication
0.000195
Ac-LLLLRAKR-NH2
pH and temperature not specified in the publication
0.000083
Ac-LLLLRKKR-NH2
pH and temperature not specified in the publication
0.000088
Ac-LLLLRRKR-NH2
pH and temperature not specified in the publication
0.000022
Ac-LLLLRVKR-NH2
pH and temperature not specified in the publication