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3.4.21.B24: proprotein convertase 4

This is an abbreviated version!
For detailed information about proprotein convertase 4, go to the full flat file.

Word Map on EC 3.4.21.B24

Reaction

cleaves hormones at pairs of basic amino acid residues =

Synonyms

More, PC4, PC4A, PCSK4, proprotein convertase 4, proprotein convertase PC4, proprotein convertase PC4/PCSK4, proprotein convertase subtilisin/kexin type 4, proprotein convertase subtilisin/kexin-like 4, S08.074

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B24 proprotein convertase 4

Natural Substrates Products

Natural Substrates Products on EC 3.4.21.B24 - proprotein convertase 4

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
pro-insulin growth factor + H2O
?
show the reaction diagram
-
-
-
?
proform acrosin-binding protein + H2O
mature acrosin-binding protein + ?
show the reaction diagram
a sperm fertilization molecule located in the acrosomal matrix, the enzyme activates the substrate by processing from a 58.5 kDa precursor to a 27.5 kDa mature form
-
-
?
proform IGF-2 + H2O
mature IGF-2 + ?
show the reaction diagram
Q6KW60
-
-
-
?
additional information
?
-