3.4.21.B21: trepolisin

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For detailed information about trepolisin, go to the full flat file.

Reaction

chymotrypsin-like protease, cleaves peptide bonds containing phenylalanine and proline =

Synonyms

chymotrypsin-like protease, chymotrypsin-like proteinase, CTLP, dentilisin, PrtP, PrtP protease, S08.024, Td chymotrypsin-like protease, Td-CTLP

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B21 trepolisin

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Results	in table
2	Activating Compound
2	AA Sequence
4	Application
1	CAS Registry Number
5	Cloned(Commentary)
1	Expression
19	General Information
15	Inhibitors
8	Localization
1	Metals/Ions
12	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
33	Organism
5	pH Optimum
1	pI Value
11	Protein Variants
3	Purification (Commentary)
1	Reaction
6	Reaction Type
21	Reference
1	Renatured (Commentary)
2	Specific Activity [micromol/min/mg]
51	Substrates and Products (Substrate)
2	Subunits
36	Synonyms
3	Temperature Optimum [°C]
1	Temperature Stability [°C]

Purification

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Purification on EC 3.4.21.B21 - trepolisin

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PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

Treponema denticola

P96091

673984

nickel affinity column chromatography

Treponema denticola

-

708938

rapidly purified by sonication, SDS-PAGE, gel filtration, pressure filtration, 101fold purified by ion-exchange chromatography followed by gel filtration

Treponema denticola

-

673907