3.4.21.B2: granzyme M
This is an abbreviated version!
For detailed information about granzyme M, go to the full flat file.
Word Map on EC 3.4.21.B2
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3.4.21.B2
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lymphocyte
-
granule
-
killer
-
perforin
-
medicine
-
cell-mediated
-
virus-infected
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cytolysis
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pore-forming
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caspase-independent
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thiobenzyl
-
serpins
-
perforin-dependent
-
m-mediated
-
norleucine
-
noncytotoxic
- 3.4.21.B2
- lymphocyte
- granule
-
killer
- perforin
- medicine
-
cell-mediated
-
virus-infected
-
cytolysis
-
pore-forming
-
caspase-independent
-
thiobenzyl
- serpins
-
perforin-dependent
-
m-mediated
- norleucine
-
noncytotoxic
Reaction
endopeptidase activity. Cleaves substrates containing a methionine side chain at P1 =
Synonyms
Granzyme M, GrM, GrzM, Gzm M, GZmM, hGzmM, hMet-1, Met-ase-1, S01.139
ECTree
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Metals Ions
Metals Ions on EC 3.4.21.B2 - granzyme M
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additional information
in Gzm M there are cationic sites, cs1 and cs2, that may participate in binding of Gzm M to the cell surface, thereby promoting its uptake and eventual release into the cytoplasm
additional information
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in Gzm M there are cationic sites, cs1 and cs2, that may participate in binding of Gzm M to the cell surface, thereby promoting its uptake and eventual release into the cytoplasm