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3.4.21.B12: prostase

This is an abbreviated version!
For detailed information about prostase, go to the full flat file.

Word Map on EC 3.4.21.B12

Reaction

proteolysis of polypeptides =

Synonyms

EM serine proteinase 1, EMSP1, enamel matrix serine protease 1, HK4, K4, kallikrein 1-related peptidase 4, kallikrein 4, kallikrein-4, kallikrein-4 proteinase, kallikrein-like protein 1, kallikrein-related peptidase, kallikrein-related peptidase 4, kallikrein-related peptidase-4, KLK, KLK-4 proteinase, KLK-L1, KLK4, More, peptidase S01.251, prostase, prostate cancer serine protease, PRSS17, S01.251, serine protease 1, serine protease 17, tissue kallikrein-related peptidase 4

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B12 prostase

Turnover Number

Turnover Number on EC 3.4.21.B12 - prostase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
7.9
(Abz)-SKGR-SLIGK(N-[2,4-dintrophenyl]ethylenediamine)-Asp-OH
-
-
1.8
benzyl-FVR-p-nitroanilide
-
thermolysin activated recombinant KLK4
0.0078
VLK-7-amido-4-methylcoumarin
-
pH 8.0, 37°C
0.033
VPR-7-amido-4-methylcoumarin
-
pH 8.0, 37°C
3.64
Z-FVR-p-nitroanilide
-
in 50 mM HEPES (pH 7.0), 150 mM NaCl, 10 mM CaCl2 buffer, at 25°C
3.64
Z-Phe-Val-Arg-p-nitroanilide
-
monomeric K4