3.4.21.B10: neurosin

This is an abbreviated version!
For detailed information about neurosin, go to the full flat file.

Word Map on EC 3.4.21.B10

3.4.21.B10

kallikreins

trypsin-like

medicine

klk8

par1

diagnostics

immunofluorometric

Reaction

proteolytic cleavage of polypeptides =

Synonyms

GK, hK6, KAL-B, kallikrein 6, kallikrein-6, kallikrein-related peptidase, kallikrein-related peptidase 6, KLK6, KRP/hK6, myelencephalonspecific protease, neurosin, protease M, S01.236, serine protease 18, serine protease 9, SP59, tissue kallikrein 6, zyme

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.B10 neurosin

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Results	in table
16	Activating Compound
4	AA Sequence
22	Application
2	CAS Registry Number
31	Cloned(Commentary)
4	Crystallization (Commentary)
569	Disease/ Diagnostics
9	Expression
26	General Information
11	IC50 Value
46	Inhibitors
22	kcat/KM [mM/s]
3	Ki Value [mM]
41	KM Value [mM]
11	Localization
1	Metals/Ions
7	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
177	Organism
2	pH Range
8	Posttranslational Modification
6	Protein Variants
8	Purification (Commentary)
2	Reaction
1	Reaction Type
62	Reference
1	Renatured (Commentary)
153	Source Tissue
99	Substrates and Products (Substrate)
3	Subunits
118	Synonyms
40	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.4.21.B10 - neurosin

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alpha-synuclein + H2O

2 entries

amyloid precursor proteins + H2O

Homo sapiens

Q92876

enzyme may play a role in development of Alzheimer's disease

647332

plasminogen + H2O

Homo sapiens

the enzyme is regulated by an autoactivation/autoinactivation mechanism. Mature hK67 displays a trypsin-like activity against human plasminogen, the putative physiological substrate

664263

polypeptide + H2O

peptides

Homo sapiens

Q92876

647332

proform protease activated receptor 1 + H2O

mature protease activated receptor 1 + ?

2 entries

proform protease activated receptor 2 + H2O

mature protease activated receptor 2 + ?

2 entries

additional information

3 entries