3.4.21.B10: neurosin

This is an abbreviated version!
For detailed information about neurosin, go to the full flat file.

Reaction

proteolytic cleavage of polypeptides =

Synonyms

GK, hK6, KAL-B, kallikrein 6, kallikrein-6, kallikrein-related peptidase, kallikrein-related peptidase 6, KLK6, KRP/hK6, myelencephalonspecific protease, neurosin, protease M, S01.236, serine protease 18, serine protease 9, SP59, tissue kallikrein 6, zyme

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B10 neurosin

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Results	in table
16	Activating Compound
4	AA Sequence
22	Application
2	CAS Registry Number
31	Cloned(Commentary)
4	Crystallization (Commentary)
569	Disease/ Diagnostics
9	Expression
26	General Information
11	IC50 Value
46	Inhibitors
22	kcat/KM [mM/s]
3	Ki Value [mM]
41	KM Value [mM]
11	Localization
1	Metals/Ions
7	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
177	Organism
2	pH Range
8	Posttranslational Modification
6	Protein Variants
8	Purification (Commentary)
2	Reaction
1	Reaction Type
62	Reference
1	Renatured (Commentary)
153	Source Tissue
99	Substrates and Products (Substrate)
3	Subunits
118	Synonyms
40	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.4.21.B10 - neurosin

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0018

2-[[4-(aminomethyl)phenyl]carbamoyl]-1-[(1-benzyl-1H-imidazol-2-yl)methyl]-3-hydroxypyridinium

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0038

4-amino-N-[4-(aminomethyl)phenyl]-2-hydroxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0135

fukugetin

Homo sapiens

-

at pH 7.5 and 37°C

752984

0.0086

N-[4-(aminomethyl)phenyl]-2-hydroxy-3-methoxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0206

N-[4-(aminomethyl)phenyl]-2-hydroxy-4-methoxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0135

N-[4-(aminomethyl)phenyl]-3-chloro-2-hydroxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0018

N-[4-(aminomethyl)phenyl]-3-[(1-benzyl-1H-imidazol-2-yl)methoxy]pyridine-2-carboxamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0106

N-[4-(aminomethyl)phenyl]-4-(dimethylamino)-2-hydroxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0078

N-[4-(aminomethyl)phenyl]-4-chloro-2-hydroxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0129

N-[4-(aminomethyl)phenyl]-4-ethoxy-2-hydroxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428

0.0003

N-[4-(aminomethyl)phenyl]-5-tert-butyl-2-hydroxybenzamide

Homo sapiens

Q92876

pH and temperature not specified in the publication

731428