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3.4.21.99: spermosin

This is an abbreviated version!
For detailed information about spermosin, go to the full flat file.

Word Map on EC 3.4.21.99

Reaction

hydrolyses arginyl bonds, preferably with Pro in the P2 position =

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.99 spermosin

Inhibitors

Inhibitors on EC 3.4.21.99 - spermosin

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5-pyrrolidone-2-carboxyl-Leu-DL-arginal
-
0.01 mM, 25% inhibition
Aprotinin
-
weak
benzamidine
-
-
benzyloxycarbonyl-Val-Pro-Arg-H
-
-
dansyl-Leu-DL-arginal
-
0.01 mM, 24% inhibition
dansyl-Val-Pro-Arg-H
-
-
diisopropyl fluorophosphate
-
-
Gly-Val-Arg-CH2Cl
-
-
Hg2+
-
1 mM, strong inhibition
leupeptin
-
weak
N-acetyl-Leu-Leu-arginal
N-benzoyl-Leu-arginal
-
0.01 mM, 15% inhibition
N-benzyloxycarbonyl-Phe-Leu-arginal
-
0.01 mM, 93% inhibition
N-benzyloxycarbonyl-Val-Pro-arginal
-
0.01 mM, 99% inhibition
o-nitrophenyl-Leu-arginal
-
0.01 mM, 52% inhibition
ovomucoid
-
-
-
p-aminobenzamidine
-
-
p-nitrobenzyl-Leu-arginal
-
0.01 mM, 26% inhibition
peptidyl-Arg-H
-
-
phenylmethanesulfonyl fluoride
-
-
Pro-Leu-arginal
-
0.01 mM, 27% inhibition
Soybean trypsin inhibitor
-
Val-Pro-Arg-CH2Cl
-
-
Zn2+
-
1 mM, strong inhibition