3.4.21.84: limulus clotting factor C

This is an abbreviated version, for detailed information about limulus clotting factor C, go to the full flat file.

Reaction

Selective cleavage of -Arg103-/-Ser- and -Ile124-/-Ile- bonds in limulus clotting factor B to form factor _overbar_B_. Cleavage of -Pro-Arg-/- bonds in synthetic substrates =

Synonyms

CrFC, Factor C, IscW_ISCW002489, Limulus factor C

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.84 limulus clotting factor C

Reference

Reference on EC 3.4.21.84 - limulus clotting factor C

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tokunaga, F.; Nakajima, H.; Iwanaga, S.
Further studies on lipopolysaccharide-sensitive serine protease zymogen (factor C): its isolation from Limulus polyphemus hemocytes and identification as an intracellular zymogen activated by alpha-chymotrypsin, not by trypsin
J. Biochem.
109
150-157
1991
Limulus polyphemus, Tachypleus tridentatus
Manually annotated by BRENDA team
Nakamura, T.; Morita, T.; Iwanaga, S.
Lipopolysaccharide-sensitive serine-protease zymogen (factor C) found in Limulus hemocytes. Isolation and characterization
Eur. J. Biochem.
154
511-521
1986
Limulus polyphemus, Tachypleus sp.
Manually annotated by BRENDA team
Muta, T.; Miyata, T.; Misumi, Y.; Tokunaga, F.; Nakamura, T.; Toh, Y.; Ikehara, Y.; Iwanaga, S.
Limulus factor C. An endotoxin-sensitive serine protease zymogen with a mosaic structure of complement-like, epidermal growth factor-like, and lectin-like domains
J. Biol. Chem.
266
6554-6561
1991
Limulus sp.
Manually annotated by BRENDA team
Wang, L.; Ho, B.; Ding, J.L.
Transciptional regulation of limulus factor C
J. Biol. Chem.
278
49428-49437
2003
Carcinoscorpius rotundicauda (Q26422)
Manually annotated by BRENDA team
Alwis, K.U.; Milton, D.K.
Recombinant factor C assay for measuring endotoxin in house dust: comparison with LAL, and (1->3)-beta-D-glucans
Am. J. Ind. Med.
49
296-300
2006
Limulus sp.
Manually annotated by BRENDA team
Kawabata, S.; Muta, T.; Iwanaga, S.
Limulus coagulation factor C
Handbook of proteolytic enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner, J. F. , eds. ) Academic Press
2nd. ed.
1740-1742
2004
Tachypleus sp.
-
Manually annotated by BRENDA team
Urbanova, V.; Hartmann, D.; Grunclova, L.; Sima, R.; Flemming, T.; Hajdusek, O.; Kopacek, P.
IrFC - an Ixodes ricinus injury-responsive molecule related to Limulus Factor C
Dev. Comp. Immunol.
46
439-447
2014
Ixodes ricinus
Manually annotated by BRENDA team