3.4.21.81: Streptogrisin B

This is an abbreviated version!
For detailed information about Streptogrisin B, go to the full flat file.

Reaction

Hydrolysis of proteins with trypsin-like specificity =

Synonyms

More, Pronase B, protease B, Proteinase B, Proteinase, Streptomyces griseus serine B, Serine proteinase B, SGPB, SprB, Streptogrisin B, Streptomyces griseus peptidase B, Streptomyces griseus protease B, Streptomyces griseus proteinase 1, Streptomyces griseus proteinase B

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.81 Streptogrisin B

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
122	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
9	Crystallization (Commentary)
1	General Stability
12	Inhibitors
4	kcat/KM [mM/s]
9	KM Value [mM]
1	Localization
4	Molecular Weight [Da]
2	Organic Solvent Stability
26	Organism
27	PDB ID
6	pH Optimum
1	Posttranslational Modification
6	Protein Variants
5	Purification (Commentary)
1	Reaction
2	Reaction Type
25	Reference
1	Renatured (Commentary)
2	Source Tissue
27	Substrates and Products (Substrate)
3	Subunits
20	Synonyms
1	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
10	Turnover Number [1/s]

Inhibitors

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Inhibitors on EC 3.4.21.81 - Streptogrisin B

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Inhibitor Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

Bovine pancreatic trypsin inhibitor

Streptomyces griseus

-

Kunitz

29766

-

N-tert-Butyloxycarbonyl-glycyl-L-leucyl-L-phenylalanine chloromethyl ketone

Streptomyces griseus

-

-

29774

N-tert-Butyloxycarbonyl-L-alanylglycyl-L-phenylalanine chloromethyl ketone

Streptomyces griseus

-

-

29774

protein inhibitor S13D14Y15-OMTKY3

Streptomyces griseus

P00777

a OMTKY3 mutant variant, recombinantly produced in Escherichia coli strain RV308 and purified, strong inhibition, overview

731812

-

protein inhibitor S13D14Y15G18I19K21-OMTKY3

Streptomyces griseus

P00777

a OMTKY3 mutant variant, recombinantly produced in Escherichia coli strain RV308 and purified, strong inhibition, overview. S13D14Y15G18I19K21 OMTKY3 inhibits Streptomyces griseus protease B 10times more strongly than Streptomyces griseus protease A, EC 3.4.21.80

731812

-

Soybean trypsin inhibitor

Streptomyces griseus

-

-

29766

-

Squash inhibitor

Streptomyces griseus

-

-

29771

-

Streptomyces subtilisin inhibitor

Streptomyces griseus

-

-

29766

-

Third domain of the ovomucoid inhibitor from turkey

Streptomyces griseus

-

-

29769

-

Turkey ovomucoid third domain

Streptomyces griseus

-

OMTKY3, inhibitor for serine peptidases

683776

-

additional information

3 entries

-

additional information

Streptomyces griseus

-

the enzyme is active in presence of guanidinium chloride

29776

-

additional information

Streptomyces griseus

-

design of inhibitors based on turkey ovomucoid third domain OMTKY3. Variant 13D14Y15G18I19K21-OMTKY3 displays a Gly residue in position P1 and represents the strongest possible inhibitor due to consensus contacts to the enzyme. Inhibitor has significantly higher DeltaGo value for protease B than that for protease A and inhibits protease B 10 times more strongly than protease A; OMTKY3 inhibitor variant screening, overview

731812

-

additional information

Streptomyces griseus

P00777

design of inhibitors based on turkey ovomucoid third domain OMTKY3. Variant 13D14Y15G18I19K21-OMTKY3 displays a Gly residue in position P1 and represents the strongest possible inhibitor due to consensus contacts to the enzyme. Inhibitor has significantly higher DeltaGo value for protease B than that for protease A and inhibits protease B 10 times more strongly than protease A; OMTKY3 inhibitor variant screening, overview

731812

-