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3.4.21.77: semenogelase

This is an abbreviated version!
For detailed information about semenogelase, go to the full flat file.

Word Map on EC 3.4.21.77

Reaction

Preferential cleavage: -Tyr-/- =

Synonyms

7S nerve growth factor gamma chain, antigen (human clone lambdaHPSA-1 prostate-specific protein moiety reduced), antigen PSA (human clone 5P1 protein moiety reduced), antigen PSA (human prostate-specific), gama-SM protein, gamma-NGF, gamma-seminoglycoprotein (human protein moiety reduced), gamma-seminoprotein, gamma-SM, GK3, glandular kallikrein, glandular kallikrein 3, hK3/PSA, K3, K4, kallikrein 3, kallikrein-related peptidase 3, kallikrein-related peptidase-3, KLK3, P-30 antigen, prostate specific antigen, prostate stem cell antigen, prostate-specific antigen, prostate-specific antigen kallikrein, Prostate-specific membrane antigen, PSA, PSA-SV5, PSCA, PSMA, S01.162, seminal proteinase, seminin, six-transmembrane epithelial antigen of the prostate, STEAP, tissue kallikrein

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.77 semenogelase

Molecular Weight

Molecular Weight on EC 3.4.21.77 - semenogelase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
160000
-
Western blotting of PSA-spiked mouse serum
200000
-
Western blotting of PSA-spiked mouse serum
25000
x * 25000, Western blot analysis and SDS-PAGE. x * 22500-35500, zymographic assay
26080
26500
-
calculation from amino acid sequence
28000
-
-
28110 - 30000
-
inactive zymogen peak 2, gel filtration, SDS-PAGE and mass spectrometry
28880 - 30000
-
active mature enzyme, gel filtration and mass spectrometry
30000
-
calculated from the amino acid composition of isolated prostate-specific antigen and proteinase
33000
34000
36000
-
x * 36000, SDS-PAGE, pro-PSA
54000
1 * 55000, SDS-PAGE, proPSA, 1 * 54000, SDS-PAGE, active PSA
55000
1 * 55000, SDS-PAGE, proPSA, 1 * 54000, SDS-PAGE, active PSA
65000
-
Western blotting of PSA-spiked mouse serum
85000
-
Western blotting of PSA-spiked mouse serum
87000
-
inactive zymogen peak 1, gel filtration