3.4.21.71: Pancreatic elastase II
This is an abbreviated version!
For detailed information about Pancreatic elastase II, go to the full flat file.
Word Map on EC 3.4.21.71
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3.4.21.71
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neutropenia
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ii-forming
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chymostatin
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netherton
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proelastase
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kostmann
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chymostatin-sensitive
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tetradecapeptide
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1-protease
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elastolytic
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ii-generating
- 3.4.21.71
- neutropenia
-
ii-forming
- chymostatin
- netherton
-
proelastase
-
kostmann
-
chymostatin-sensitive
- tetradecapeptide
-
1-protease
-
elastolytic
-
ii-generating
Reaction
Preferential cleavage: Leu-/-, Met-/- and Phe-/-. Hydrolyses elastin =
Synonyms
bovine pancreatic elastase, ELA-2, ELA2, Elastase 2, elastase-2, GICP, neutrophil elastase 2
ECTree
3.4.21.71 Pancreatic elastase IIAdvanced search results
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Substrates Products on EC 3.4.21.71 - Pancreatic elastase II
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
Gly-Ile-Asp-Val-Gln-Ile-Tyr + H2O
Gly-Ile-Asp-Val-Gln + Ile-Tyr + ?
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sequence in phenylalanine oxidase
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?
Suc-Ala-Ala-Pro-Met-p-nitroanilide + H2O
p-nitroaniline + Suc-Ala-Ala-Pro-Met
-
-
-
?
Suc-Ala-Ala-Val-Ala-p-nitroanilide + H2O
p-nitroaniline + Suc-Ala-Ala-Val-Ala
-
-
-
?
Suc-Tyr-Leu-Val-p-nitroanilide + H2O
p-nitroaniline + Suc-Tyr-Leu-Val
-
-
-
?
Somatostatin-14 + H2O
?
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hydrolytic enzyme required for intestinal digestion of food stuff, natural substrates are proteins, protein fragments and peptides, greater affinity for natural substrates than for synthetics, specifically involved in the regulation of biological functions of somatostatin-14 in the gastrointestinal tract
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?
additional information
?
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the enzyme is formed by activation of proelastase II from mammalian pancreas by trypsin, usually only one of the pancreatic elastases (see also EC 3.4.21.36) is expressed in a given species
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-
?
additional information
?
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the enzyme is formed by activation of proelastase II from mammalian pancreas by trypsin, usually only one of the pancreatic elastases (see also EC 3.4.21.36) is expressed in a given species
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-
?
additional information
?
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the enzyme is formed by activation of proelastase II from mammalian pancreas by trypsin, usually only one of the pancreatic elastases (see also EC 3.4.21.36) is expressed in a given species
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-
?
