3.4.21.65: Thermomycolin

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For detailed information about Thermomycolin, go to the full flat file.

Reaction

Rather nonspecific hydrolysis of proteins. Preferential cleavage: Ala-/-, Tyr-/-, Phe-/- in small molecule substrates =

Synonyms

EC 3.4.21.14, EC 3.4.4.16, Proteinase, Malbranchea pulchella sulfurea extracellular, Thermomycolase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.65 Thermomycolin

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Results	in table
1	AA Sequence
1	CAS Registry Number
11	General Stability
18	Inhibitors
2	KM Value [mM]
3	Localization
8	Molecular Weight [Da]
7	Organism
5	pH Optimum
8	pH Stability
3	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
1	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
24	Substrates and Products (Substrate)
4	Subunits
4	Synonyms
10	Temperature Stability [°C]
2	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.4.21.65 - Thermomycolin

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

4-Methylphenylsulfonyl fluorides

Malbranchea pulchella

-

-

29526

4-Nitrophenylsulfonyl fluorides

Malbranchea pulchella

-

-

29526

BaCl2

Malbranchea pulchella

-

weak

29526

Carboxybenzoyl halomethyl ketones

Malbranchea pulchella

-

L-Phe-CH2Cl and L-Phe-CH2Br

29526

-

CdCl2

Malbranchea pulchella

-

-

29526

CoCl2

Malbranchea pulchella

-

-

29526

CuCl2

Malbranchea pulchella

-

-

29526

DFP

Malbranchea pulchella

-

-

29526

Egg white trypsin inhibitor

Malbranchea pulchella

-

-

29526

-

HgCl2

Malbranchea pulchella

-

-

29526

Lima bean trypsin inhibitor

Malbranchea pulchella

-

-

29526

-

MgCl2

Malbranchea pulchella

-

-

29526

MnCl2

Malbranchea pulchella

-

-

29526

NiCl2

Malbranchea pulchella

-

-

29526

Phenylmethylsulfonyl fluorides

Malbranchea pulchella

-

-

29526

-

Serine protease inhibitors

Malbranchea pulchella

-

-

29531

-

Soybean trypsin inhibitor

Malbranchea pulchella

-

-

29526

-

ZnCl2

Malbranchea pulchella

-

-

29526