3.4.21.62: Subtilisin
This is an abbreviated version!
For detailed information about Subtilisin, go to the full flat file.
Reaction
Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides
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Synonyms
AcpII, Ak.1 protease, Alcalase, Alcalase 0.6L, Alcalase 2.5L, ALE1 subtilase, ALK-enzyme, Alkaline mesentericopeptidase, Alkaline protease, alkaline serine protease, ALP1, Alzwiprase, aprE, AprE51, aqualysin, Arp, AsES, Asp v 13, AtSBT1.9, Bacillopeptidase A, Bacillopeptidase B, Bacillus gibsonii alkaline protease, Bacillus subtilis alkaline proteinase Bioprase, BgAP, Bioprase AL 15, Bioprase APL 30, BLS, BPN', BprB, BprV, C1 subtilase, cold active subtilisin-like serine proteinase, Colistinase, EC 3.4.21.14, EC 3.4.4.16, Esperase, Fe protease, Fe prtS8A, Genenase I, intracellular subtilisin protease, ISP, IvaP, Kazusase, Maxatase, mesenteroicopeptidase, More, Nagarse, Opticlean, ORF2, Orientase 10B, P69 subtilase, PBANKA_1106900, PbSOPT, Peptidase, subtilo-, A, PF3D7_0507300, phytophase, PIMMS2, Protease S, Protease VIII, Protease XXVII, Proteinase K, Proteinase, Bacillus subtilis alkaline, Protin A 3L, PSP-3, psychrophilic subtilisin-like protease, S1P subtilase, SAP, SAS-1, SASP, saspase, Savinase, Savinase 16.0L, Savinase 32.0 L EX, Savinase 4.0T, Savinase 8.0L, savinaseTM, SBc, SBL, SDD1 subtilase, senescence-associated subtilisin protease, SES7, SISBT3 subtilase, SOPT, SP 266, Sspa, SSU0757, SUB1, SUB2, subC, subtilase, subtilase subfamily 1 member 9, subtilase-like protease, subtilisin, subtilisin 72, subtilisin A, Subtilisin amylosacchariticus, Subtilisin BL, subtilisin BPN, subtilisin C., subtilisin Carlsberg, subtilisin DJ-4, Subtilisin DY, Subtilisin E, subtilisin E-S7, Subtilisin GX, subtilisin JB1, subtilisin Karlsberg, Subtilisin Novo, subtilisin Pr1-like protease, subtilisin protease, subtilisin QK, Subtilisin S41, subtilisin S4I, subtilisin S88, Subtilisin Sendai, subtilisin Sph, subtilisin-like ookinete protein, subtilisin-like ookinete protein important for transmission, subtilisin-like protease, subtilisin-like protease AprV2, subtilisin-like serine protease, Subtilisn J, Subtilopeptidase, Superase, thermitase, thermo-active subtilisin-like serine protease, Thermoase, Thermoase PC 10, thermophilic thermitase, thermostable subtilisin, ThSS45, Tk-subtilisin, trans-cinnamoyl-subtilisin, V. cholerae-secreted serine protease, VC_0157, vPR
ECTree
Synonyms
Synonyms on EC 3.4.21.62 - Subtilisin
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Alkaline mesentericopeptidase
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Asp v 13
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subtilisin-like serine protease
Bacillopeptidase A
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Bacillopeptidase B
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Bacillus gibsonii alkaline protease
Bacillus subtilis alkaline proteinase Bioprase
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cold active subtilisin-like serine proteinase
EC 3.4.4.16
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formerly, part transferred
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intracellular subtilisin protease
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mesenteroicopeptidase
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Peptidase, subtilo-, A
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Proteinase, Bacillus subtilis alkaline
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psychrophilic subtilisin-like protease
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SAS-1
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extensive homology to other plant subtilisin-like serine protease
saspase
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saspase: serine proteases exhibting aspase activity
Savinase 32.0 L EX
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senescence-associated subtilisin protease
Q0WWH7
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subtilase subfamily 1 member 9
Subtilisin amylosacchariticus
subtilisin Pr1-like protease
Subtilisin Sendai
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subtilisin-like ookinete protein
subtilisin-like ookinete protein important for transmission
subtilisin-like protease AprV2
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subtilisin-like serine protease
thermo-active subtilisin-like serine protease
thermophilic thermitase
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trans-cinnamoyl-subtilisin
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acyl-enzyme covalent intermediate of the serine protese subtilisin Carlsberg
V. cholerae-secreted serine protease
AcpII
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Ak.1 protease
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Alcalase
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Alkaline protease
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alkaline serine protease
UniProt
alkaline serine protease
UniProt
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alkaline serine protease
Vibrio cholerae serotype O1 C6706
UniProt
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alkaline serine protease
UniProt
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aprE
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AtSBT1.9
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Bacillus gibsonii alkaline protease
GN111900.1
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Bacillus gibsonii alkaline protease
GN111900.1
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BgAP
GN111900.1
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cold active subtilisin-like serine proteinase
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cold active subtilisin-like serine proteinase
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EC 3.4.21.14
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formerly
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EC 3.4.21.14
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formerly included in
EC 3.4.21.14
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formerly included in
Fe protease
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Fe prtS8A
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IvaP
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IvaP
Vibrio cholerae serotype O1 C6706
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ORF2
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PbSOPT
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phytophase
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extensive homology to other plant subtilisin-like serine protease, phytaspase: a plant aspartate-specific protease
phytophase
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extensive homology to other plant subtilisin-like serine protease, phytaspase: a plant aspartate-specific protease
PIMMS2
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SAP
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SBL
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SES7
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SOPT
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subtilase
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subtilase subfamily 1 member 9
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subtilase subfamily 1 member 9
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subtilase-like protease
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subtilase-like protease
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subtilisin
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subtilisin 72
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subtilisin A
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Subtilisin amylosacchariticus
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from Bacillus subtilis var. amylosacchariticus
Subtilisin amylosacchariticus
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from Bacillus subtilis var. amylosacchariticus
Subtilisin amylosacchariticus
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from Bacillus subtilis var. amylosacchariticus
subtilisin BPN
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subtilisin Carlsberg
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651044, 653614, 653619, 685336, 685717, 685809, 686432, 688433, 688609, 689303, 689947, 707804, 709558, 732243
subtilisin DJ-4
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strain DJ-4
subtilisin DJ-4
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strain DJ-4
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Subtilisin DY
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Subtilisin E
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subtilisin E-S7
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subtilisin JB1
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subtilisin Pr1-like protease
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subtilisin Pr1-like protease
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subtilisin QK
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Subtilisin S41
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subtilisin Sph
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subtilisin-like ookinete protein
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subtilisin-like ookinete protein
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subtilisin-like ookinete protein
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subtilisin-like ookinete protein important for transmission
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subtilisin-like ookinete protein important for transmission
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subtilisin-like ookinete protein important for transmission
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
Vibrio cholerae serotype O1 C6706
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subtilisin-like serine protease
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thermo-active subtilisin-like serine protease
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thermo-active subtilisin-like serine protease
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thermo-active subtilisin-like serine protease
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thermostable subtilisin
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thermostable subtilisin
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ThSS45
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V. cholerae-secreted serine protease
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V. cholerae-secreted serine protease
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V. cholerae-secreted serine protease
Vibrio cholerae serotype O1 C6706
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V. cholerae-secreted serine protease
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VC_0157
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VC_0157
Vibrio cholerae serotype O1 C6706
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vPR
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additional information
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species variants include subtilisin BPN' (also subtilisin B, subtilopeptidase B, subtilopeptidase C, Nagarse, Nagarse proteinase, subtilisin Novo, bacterial proteinase Novo) and subtilisin Carlsberg (subtilisin A, subtilopeptidase A, alcalase Novo), similar enzymes are produced by various Bacillus subtilis strains and other Bacillus species
additional information
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synonyms of subtilisin Carlsberg: subtilisin, subtilisin A, subtilopeptidase A, alcalase Novo, synonyms of subtilisin BPN': nagarse proteinase, Nagarse, BPN', subtilopeptidase C, synonyms of subtilisin Novo: bacterial proteinase Novo, subtilisin B, subtilopeptidase B
additional information
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species variants include subtilisin BPN' (also subtilisin B, subtilopeptidase B, subtilopeptidase C, Nagarse, Nagarse proteinase, subtilisin Novo, bacterial proteinase Novo) and subtilisin Carlsberg (subtilisin A, subtilopeptidase A, alcalase Novo), similar enzymes are produced by various Bacillus subtilis strains and other Bacillus species
additional information
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synonyms of subtilisin Carlsberg: subtilisin, subtilisin A, subtilopeptidase A, alcalase Novo, synonyms of subtilisin BPN': nagarse proteinase, Nagarse, BPN', subtilopeptidase C, synonyms of subtilisin Novo: bacterial proteinase Novo, subtilisin B, subtilopeptidase B
additional information
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the commercial enzyme subtilisin BPN' from Sigma: kinetic and physical properties indicate that the commercial enzyme is probably subtilisin Carlsberg isolated from Bacillus licheniformis, much work which has been performed on commercial subtilisin BPN' from 1975 up to 1985 must be revaluated
additional information
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synonyms of subtilisin Carlsberg: subtilisin, subtilisin A, subtilopeptidase A, alcalase Novo, synonyms of subtilisin BPN': nagarse proteinase, Nagarse, BPN', subtilopeptidase C, synonyms of subtilisin Novo: bacterial proteinase Novo, subtilisin B, subtilopeptidase B