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3.4.21.59: Tryptase

This is an abbreviated version!
For detailed information about Tryptase, go to the full flat file.

Word Map on EC 3.4.21.59

Reaction

Preferential cleavage: Arg-/-, Lys-/-, but with additional information restricted specificity than trypsin =

Synonyms

alpha 1-tryptase, alpha tryptase, alpha-tryptase, basal serum tryptase, beta tryptase I, beta tryptase II, beta-tryptase, betaI-tryptase, betaII-tryptase, BLCT, bovine liver capsule tryptase, bovine mast cell tryptase, BTM, delta-tryptase, gamma-tryptase, group 2 tryptase, HAST, HMC-1 tryptase, HTbeta, human beta-tryptase, human betaII-tryptase, human lung tryptase, human mast cell tryptase, human mast cell tryptase beta I, human tryptase alpha, human tryptase beta, human tryptase beta/2, human tryptase-beta, Lung tryptase, Mast cell neutral proteinase, mast cell protease 11, mast cell protease 6, mast cell protease 7, Mast cell protease II, mast cell protease-6, Mast cell proteinase II, mast cell specific tryptase, Mast cell tryptase, mast cell tryptase beta, mast cell-derived tryptase, mast cell-specific protease, mast cell-specific tryptase, MC protease 6, MC protease 7, MC protease-6, MC tryptase, MCP-11, MCP-6, MCP-7, Mcpt6, MCT, mMCP-6, mouse mast cell protease 6, mouse mast cell protease-6, Pituitary tryptase, Proteinase, mast cell neutral, Proteinase, mast cell serine, II, Proteinase, mast cell serine, tryptase, Prss31, Rat mast cell protease II, rHT, S-tryptase, sBT, serine protease tryptase, serum baseline tryptase, serum mast cell tryptase, serum tryptase, Skin tryptase, TMT, TPSAB1, TPSB2, transmembrane tryptase, tryptase, tryptase alpha, tryptase alpha-1, tryptase beta, tryptase beta-1, tryptase beta-2, Tryptase M, Tryptase, skin, tryptase-2, tryptase-beta, tryptase-beta1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.59 Tryptase

Turnover Number

Turnover Number on EC 3.4.21.59 - Tryptase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
141
Ac-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
367
Ac-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
1.1 - 3.5
Ac-PANK-AAC
0.97 - 0.99
Ac-PRNK-AAC
3.8 - 21.8
Ac-PRNR-AAC
378
Ac-Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.99 - 1.1
Ac-PRTK-AAC
187
Ala-Ala-Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
233
Ala-Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
159
Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.8
Benzyloxycarbonyl-Ala-Arg-Arg 4-methylcoumarin 7-amide
-
-
0.05
benzyloxycarbonyl-Arg 4-methylcoumarin 7-amide
-
-
5.35 - 5.52
benzyloxycarbonyl-Arg 4-nitroanilide
104 - 107
Benzyloxycarbonyl-Gly-Arg 4-trifluoromethylcoumarin 7-amide
551 - 553
Benzyloxycarbonyl-Gly-Pro-Arg 4-nitroanilide
2040
Benzyloxycarbonyl-L-Ala-L-Arg-L-Arg 4-methylcoumarin 7-amide
-
-
1870
benzyloxycarbonyl-L-Ala-L-Leu-L-Lys-7-amido-4-methylcoumarin
-
-
-
3290
Benzyloxycarbonyl-L-Ala-L-Lys-L-Arg 4-methylcoumarin 7-amide
-
-
1520
Benzyloxycarbonyl-L-Ala-L-Lys-L-Lys 4-methylcoumarin 7-amide
-
-
45.7
Benzyloxycarbonyl-Lys-Arg 4-trifluoromethylcoumarin 7-amide
-
skin and lung enzyme
46.3
bovine prothrombin
-
-
-
0.03 - 8.9
Bz-Arg-p-nitroanilide
97 - 170
D-Ile-Pro-Arg-4-nitroanilide
3 - 40
D-Ile-Pro-Arg-p-nitroanilide
24.1 - 59.5
D-Phe-Pip-Arg-p-nitroanilide
2.8 - 5.3
D-Pro-Phe-Arg-p-nitroanilide
0.833 - 31
D-Val-Leu-Arg-p-nitroanilide
9 - 183
Glu-Gly-Arg-p-nitroanilide
1.5 - 56.9
Glu-Pro-Arg-p-nitroanilide
199
Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
15.2 - 2630
MeOCO-Nle-Gly-Arg-p-nitroanilide
23.5
N-(p-tosyl)-Gly-Pro-Arg-4-nitroanilide
pH 8.0, 22°C
12
N-(p-tosyl)-Gly-Pro-Lys-p-nitroanilide
pH 8.0, 22°C
1.9 - 21
N-p-tosyl-Gly-Pro-Arg-p-nitroanilide
0.74 - 540
N-p-tosyl-Gly-Pro-Lys-p-nitroanilide
435
Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
5.8 - 87
S-2288
7
t-butyloxycarbonyl-Phe-Ser-Arg-4-methyl-coumarin 7-amide
-
pH 8.0, 30°C
0.5
Tert-Butyloxycarbonyl-Gly-Lys-Arg 4-methylcoumarin 7-amide
-
-
1.4
tert-butyloxycarbonyl-L-Val-L-Pro-L-Arg-4-methylcoumarin 7-amide
-
-
2.2
tert-butyloxycarbonyl-Phe-Ser-Arg 4-methylcoumarin 7-amide
-
-
27.9 - 75.5
tosyl-Gly-Pro-Lys-p-nitroanilide
1.9 - 10.3
Z-D-Arg-Gly-Arg-p-nitroanilide
additional information
additional information
-