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3.4.21.59: Tryptase

This is an abbreviated version!
For detailed information about Tryptase, go to the full flat file.

Word Map on EC 3.4.21.59

Reaction

Preferential cleavage: Arg-/-, Lys-/-, but with additional information restricted specificity than trypsin =

Synonyms

alpha 1-tryptase, alpha tryptase, alpha-tryptase, basal serum tryptase, beta tryptase I, beta tryptase II, beta-tryptase, betaI-tryptase, betaII-tryptase, BLCT, bovine liver capsule tryptase, bovine mast cell tryptase, BTM, delta-tryptase, gamma-tryptase, group 2 tryptase, HAST, HMC-1 tryptase, HTbeta, human beta-tryptase, human betaII-tryptase, human lung tryptase, human mast cell tryptase, human mast cell tryptase beta I, human tryptase alpha, human tryptase beta, human tryptase beta/2, human tryptase-beta, Lung tryptase, Mast cell neutral proteinase, mast cell protease 11, mast cell protease 6, mast cell protease 7, Mast cell protease II, mast cell protease-6, Mast cell proteinase II, mast cell specific tryptase, Mast cell tryptase, mast cell tryptase beta, mast cell-derived tryptase, mast cell-specific protease, mast cell-specific tryptase, MC protease 6, MC protease 7, MC protease-6, MC tryptase, MCP-11, MCP-6, MCP-7, Mcpt6, MCT, mMCP-6, mouse mast cell protease 6, mouse mast cell protease-6, Pituitary tryptase, Proteinase, mast cell neutral, Proteinase, mast cell serine, II, Proteinase, mast cell serine, tryptase, Prss31, Rat mast cell protease II, rHT, S-tryptase, sBT, serine protease tryptase, serum baseline tryptase, serum mast cell tryptase, serum tryptase, Skin tryptase, TMT, TPSAB1, TPSB2, transmembrane tryptase, tryptase, tryptase alpha, tryptase alpha-1, tryptase beta, tryptase beta-1, tryptase beta-2, Tryptase M, Tryptase, skin, tryptase-2, tryptase-beta, tryptase-beta1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.59 Tryptase

KM Value

KM Value on EC 3.4.21.59 - Tryptase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.05
Ac-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.062
Ac-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.1105 - 0.1333
Ac-PANK-AAC
0.0089 - 0.0145
Ac-PRNK-AAC
0.0165 - 0.0186
Ac-PRNR-AAC
0.071
Ac-Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.0147 - 0.0234
Ac-PRTK-AAC
0.04
Ala-Ala-Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.053
Ala-Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.1
Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.0002
Benzyloxycarbonyl-Ala-Arg-Arg 4-methylcoumarin 7-amide
-
-
0.0231
benzyloxycarbonyl-Arg 4-methylcoumarin 7-amide
-
-
0.0409
Benzyloxycarbonyl-L-Ala-L-Arg-L-Arg 4-methylcoumarin 7-amide
-
-
0.323
benzyloxycarbonyl-L-Ala-L-Leu-L-Lys-7-amido-4-methylcoumarin
-
-
-
0.0138
Benzyloxycarbonyl-L-Ala-L-Lys-L-Arg 4-methylcoumarin 7-amide
-
-
0.0148
Benzyloxycarbonyl-L-Ala-L-Lys-L-Lys 4-methylcoumarin 7-amide
-
-
0.0023
bovine prothrombin
-
-
-
0.3 - 5
Bz-Arg-p-nitroanilide
0.062 - 0.081
D-Ile-Pro-Arg-4-nitroanilide
0.4 - 8.2
D-Ile-Pro-Arg-p-nitroanilide
0.7 - 0.79
D-Phe-Pip-Arg-p-nitroanilide
1.64 - 13.5
D-Pro-Phe-Arg-p-nitroanilide
1.12 - 3.49
D-Val-Leu-Arg-p-nitroanilide
5.03 - 10.5
Glu-Gly-Arg-p-nitroanilide
0.37 - 0.64
Glu-Pro-Arg-p-nitroanilide
0.111
Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.58 - 1.16
MeOCO-Nle-Gly-Arg-p-nitroanilide
0.922
N-(p-tosyl)-Gly-Pro-Arg-4-nitroanilide
pH 8.0, 22°C
2.849
N-(p-tosyl)-Gly-Pro-Lys-p-nitroanilide
pH 8.0, 22°C
0.049 - 0.12
N-p-tosyl-Gly-Pro-Arg-p-nitroanilide
0.19 - 4.2
N-p-tosyl-Gly-Pro-Lys-p-nitroanilide
0.044
Pro-Ile-Arg-Asn-Lys-5-amino-2-nitrobenzoylamide
-
-
0.32 - 1.6
S-2288
0.043
t-butyloxycarbonyl-Phe-Ser-Arg-4-methyl-coumarin 7-amide
-
pH 8.0, 30°C
0.0046
Tert-Butyloxycarbonyl-Gly-Lys-Arg 4-methylcoumarin 7-amide
-
-
0.029
tert-butyloxycarbonyl-Phe-Ser-Arg 4-methylcoumarin 7-amide
-
-
0.031
tert-butyloxycarbonyl-Val-Pro-Arg 4-methylcoumarin 7-amide
-
-
0.35 - 0.49
tosyl-Gly-Pro-Lys-p-nitroanilide
0.04 - 0.36
Z-D-Arg-Gly-Arg-p-nitroanilide
additional information
additional information
-