3.4.21.46: complement factor D

This is an abbreviated version!
For detailed information about complement factor D, go to the full flat file.

Word Map on EC 3.4.21.46

3.4.21.46

angiogenesis

angiogenic

vessel

metastasis

neovascularization

hypoxia

artery

hypoxia-inducible

necrosis

retinal

antiangiogenic

umbilical

bevacizumab

microvessels

vein

capillary

factor-1

huvecs

vegfr-2

collagen

vasculature

retinopathy

eyes

ovarian

macular

tumour

tube

microvascular

mesenchymal

anti-vegf

lymphatic

receptor-2

pro-angiogenic

bfgf

intravitreal

progression-free

edema

choroid

metalloproteinase

endothelium

hypertension

sprout

matrigel

paracrine

lymph

hif-1alpha

mmp-9

sunitinib

drug development

sorafenib

vitreous

medicine

Reaction

selective cleavage of Arg-/-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor =

Synonyms

28 kDa protein, adipocyte, Adipsin, alternative complement pathway component Factor D, C3 convertase activator, C3 proactivator convertase, CFD, complement factor D/adipsin and kallikrein-like serine protease, convertase, C3 proactivator, Df, Df protein, endogenous vascular elastase, esterase, properdin factor D, factor D, factor D (complement), fD, PDGF-D, platelet-derived growth factor D, PoDAK, vascular endothelial growth factor, vascular endothelial growth factor D, VEGF-D

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.46 complement factor D

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Results	in table
4	Activating Compound
169	AA Sequence
8	Application
1	CAS Registry Number
14	Cloned(Commentary)
11	Crystallization (Commentary)
77827	Disease/ Diagnostics
9	Expression
21	General Information
1	General Stability
41	IC50 Value
53	Inhibitors
8	KM Value [mM]
3	Localization
1	Metals/Ions
8	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
189	Organism
103	PDB ID
3	pI Value
4	Posttranslational Modification
28	Protein Variants
18	Purification (Commentary)
1	Reaction
1	Reaction Type
50	Reference
77	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
41	Substrates and Products (Substrate)
7	Subunits
49	Synonyms
8	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.21.46 - complement factor D

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28 kDa protein, adipocyte

Adipsin

3 entries

alternative complement pathway component Factor D

2 entries

C3 convertase activator

C3 proactivator convertase

CFD

3 entries

complement factor D/adipsin and kallikrein-like serine protease

Paralichthys olivaceus

C9D6Z6

708533

convertase, C3 proactivator

Df protein

endogenous vascular elastase

esterase, properdin factor D

factor D

8 entries

factor D (complement)

Homo sapiens

669356

PDGF-D

Homo sapiens

698194, 707940, 754127

platelet-derived growth factor D

Homo sapiens

698194, 754127

PoDAK

Paralichthys olivaceus

C9D6Z6

708533

vascular endothelial growth factor

Homo sapiens

O43915

698902

vascular endothelial growth factor D

2 entries

VEGF-D

2 entries