3.4.21.46: complement factor D
This is an abbreviated version!
For detailed information about complement factor D, go to the full flat file.
Word Map on EC 3.4.21.46
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3.4.21.46
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angiogenesis
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angiogenic
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vessel
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metastasis
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neovascularization
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hypoxia
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artery
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hypoxia-inducible
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necrosis
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retinal
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antiangiogenic
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umbilical
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bevacizumab
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microvessels
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vein
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capillary
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factor-1
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huvecs
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vegfr-2
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collagen
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vasculature
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retinopathy
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eyes
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ovarian
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macular
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tumour
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tube
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microvascular
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mesenchymal
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anti-vegf
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lymphatic
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receptor-2
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pro-angiogenic
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bfgf
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intravitreal
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progression-free
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edema
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choroid
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metalloproteinase
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endothelium
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hypertension
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sprout
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matrigel
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paracrine
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lymph
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hif-1alpha
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mmp-9
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sunitinib
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drug development
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sorafenib
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vitreous
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medicine
- 3.4.21.46
- angiogenesis
-
angiogenic
- vessel
- metastasis
- neovascularization
- hypoxia
- artery
-
hypoxia-inducible
- necrosis
- retinal
-
antiangiogenic
-
umbilical
-
bevacizumab
-
microvessels
- vein
- capillary
- factor-1
- huvecs
- vegfr-2
- collagen
- vasculature
- retinopathy
- eyes
- ovarian
-
macular
- tumour
- tube
-
microvascular
- mesenchymal
-
anti-vegf
- lymphatic
- receptor-2
-
pro-angiogenic
- bfgf
-
intravitreal
-
progression-free
- edema
- choroid
- metalloproteinase
- endothelium
- hypertension
-
sprout
- matrigel
-
paracrine
- lymph
- hif-1alpha
- mmp-9
- sunitinib
- drug development
- sorafenib
- vitreous
- medicine
Reaction
selective cleavage of Arg-/-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor =
Synonyms
28 kDa protein, adipocyte, Adipsin, alternative complement pathway component Factor D, C3 convertase activator, C3 proactivator convertase, CFD, complement factor D/adipsin and kallikrein-like serine protease, convertase, C3 proactivator, Df, Df protein, endogenous vascular elastase, esterase, properdin factor D, factor D, factor D (complement), fD, PDGF-D, platelet-derived growth factor D, PoDAK, vascular endothelial growth factor, vascular endothelial growth factor D, VEGF-D
ECTree
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Specific Activity
Specific Activity on EC 3.4.21.46 - complement factor D
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additional information
additional information
complement factor D identified as mediator of rosette formation of parasitized red blood cells pRBC, induces 30 to 40% of de novo rosetting, de novo rosetting experiments described
additional information
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immunohistological detection between day 7 and 35 post-fertilization, transcripts detected at day 28, peaking at day 84 and 98 post-fertilization
additional information
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immunohistological detection in homogenates from all sampled time-points including day 0 post-fertilization, transcripts detected at day 28, peaking at day 84 and 98 post-fertilization
additional information
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protein not detected until day 77 post-fertilization, transcription starting at day 28 and peaking at day 84 and 98 post-fertilization
additional information
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transcript levels steadily increased from day 28 post-fertilization to hatch, immunohistological detection of Df protein in homogenates from all sampled time-points including day 0 post-fertilization
additional information
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transcripts of complement factor D steadily increased from day 28 post-fertilization to hatch, mRNA detected at day 28, peaking at day 84 and 98 post-fertilization observed, immunohistological detection of Df protein in homogenates from all sampled time-points including day 0 post-fertilization