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3.4.21.45: complement factor I

This is an abbreviated version!
For detailed information about complement factor I, go to the full flat file.

Word Map on EC 3.4.21.45

Reaction

Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage =

Synonyms

C3b inactivator, C3b/C4b inactivator, C3bINA, CFI, complement C3b inactivator, complement C3b/C4b inactivator, complement C4b inactivator, complement C4bi, complement compoment C3b inactivator, complement factor I, complement inhibitor factor I, complement regulator factor I, conglutinogen-activating factor C, factor I, factor I-like activity, fI, GcIf-1, GcIf-2, GcIf-3, GcIf-4, IF, plasma protease factor I, serine protease Factor I

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.45 complement factor I

Purification

Purification on EC 3.4.21.45 - complement factor I

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
by size-exclusion chromatography
-
extracellular enzyme from serum
-
gel filtration
gel filtration, recombinant protein
gel filtration, SDS-PAGE
generation of intact form of SP domain, purifiaction by affinity chromatography on MRC-OX21-Sepharose
-
His Trap column chromatography
on Ni-NTA resin
-
recombinant and native proteins, gel filtration, SDS-PAGE
using Ni-NTA chromatography
-